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Joachim W Fluhr

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Articles 118
Citations 1540
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Recent Articles
1.
Ribeiro A, Pereira-Leite C, Rosado C, Aruci E, Colley H, Kortekaas Krohn I, et al.
JID Innov . 2025 Feb; 5(2):100340. PMID: 39925780
Skin acts as a dynamic interface with the environment. Pathological alterations in the skin barrier are associated with skin diseases. These conditions are characterized by specific impairments in epidermal barrier...
2.
Brooks S, Mahmoud R, Lin R, Fluhr J, Yosipovitch G
J Invest Dermatol . 2024 Sep; 145(3):509-521. PMID: 39243251
The acid mantle concept refers to the buffer system located in the upper stratum corneum of the skin. By sustaining an acidic environment, the acid mantle contributes to the regulation...
3.
Fluhr J, Menzel P, Schwarzer R, Nikolaeva D, Darlenski R, Albrecht M
Int J Cosmet Sci . 2024 Aug; 46(4):566-577. PMID: 39113314
Introduction: Stratum corneum (SC) is essential for skin barrier function, mitigating water loss and shielding against potentially harmful substances and allergens. The SC's lipid matrix, arranged in a lamellar structure,...
4.
Fluhr J, Darlenski R, Daehnhardt-Pfeiffer S, Albrecht M
Int J Cosmet Sci . 2024 Aug; 46(4):578-589. PMID: 39113294
Introduction: The integrity of the stratum corneum (SC) is crucial for the skin's barrier function, protecting against environmental stressors and minimizing transepidermal water loss. Advances in skincare formulations have introduced...
5.
Fluhr J, F Alexis A, Andriessen A, Ferero Barrios O, Bjerring P, Foley P, et al.
Int J Dermatol . 2024 Jul; 63(12):1676-1684. PMID: 39073154
Xerosis is highly prevalent in the population aged over 50 years and substantially impacts quality of life due to the associated stigma, related pruritus, and potential sequelae. We propose that...
6.
Maurer M, Kolkhir P, Pereira M, Siebenhaar F, Witte-Handel E, Bergmann K, et al.
Allergy . 2024 Jul; 79(9):2396-2413. PMID: 39044706
Chronic spontaneous urticaria (CSU) is a debilitating, inflammatory skin condition characterized by infiltrating immune cells. Available treatments are limited to improving the signs and symptoms. There is an unmet need...
7.
Fluhr J, Herzog L, Darlenski R, Mentel T, Zuberbier T
Acta Derm Venereol . 2024 Jun; 104:adv40127. PMID: 38887031
Heat application is known to activate transient receptor potential (TRP) channels, which play a crucial role in sensory perception, including itch. In this study, the effect of a 5-s, 49°C...
8.
Foerster-Ruhrmann U, Jurkov M, Szczepek A, Bergmann K, Fluhr J, Olze H
Biomedicines . 2024 May; 12(5). PMID: 38790987
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) exacerbated respiratory disease (N-ERD) is associated with chronic rhinosinusitis with nasal polyps (CRSwNP), asthma, and NSAID hypersensitivity. An overproduction of leukotrienes characterizes the pathomechanism of...
9.
Fluhr J, Voisard A, Nikolaeva D, Herzog L, Wiora G, Gayer J, et al.
Skin Pharmacol Physiol . 2024 May; 37(1-3):40-48. PMID: 38763134
Introduction: Non-invasive measurement of the stratum corneum hydration (SCH) with capacitance-based instrumentation is established in dermatological and cosmetic studies. We wanted to test the reliability of non-invasive self-measurements for SCH...
10.
Staubach P, Bilo B, Fluhr J, Krause K, Kulthanan K, Salman A, et al.
J Dermatolog Treat . 2024 Mar; 35(1):2329784. PMID: 38508226
Background: There is a lack of real-life safety data on treatment options for chronic urticaria in the presence of comedication and comorbidities. Methods: We present a single-center UCARE pilot study...