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Jir-Jei Yang

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Articles 9
Citations 34
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Recent Articles
1.
Lin S, Hsu Y, Yang J, Tu M
J Alzheimers Dis . 2025 Feb; 104(1):106-115. PMID: 39994969
BackgroundWhile cerebrovascular hemodynamics exhibits critical interplay with the pathogenesis of dementia, limited articles have examined the impact of vertebrobasilar (VB) hemodynamics on cerebral blood flow (CBF), and to what extent...
2.
Tu M, Huang S, Hsu Y, Yang J, Lin C, Kuo L
Sci Rep . 2024 Jan; 14(1):2570. PMID: 38297073
Identifying subcortical ischemic vascular disease (SIVD) in older adults is important but challenging. Growing evidence suggests that diffusional kurtosis imaging (DKI) can detect SIVD-relevant microstructural pathology, and a systematic assessment...
3.
Tu M, Chung H, Hsu Y, Yang J, Wu W
J Alzheimers Dis . 2023 Nov; 96(3):1329-1338. PMID: 37980672
Background: Cobalamin (Cbl) and folate are common supplements clinicians prescribe as an adjuvant therapy for dementia patients, on the presumption of their neurotrophic and/or homocysteine (Hcy) lowering effect. However, the...
4.
Altunkaya S, Huang S, Hsu Y, Yang J, Lin C, Kuo L, et al.
Front Aging Neurosci . 2022 Feb; 13:717037. PMID: 35185511
Few studies have investigated differences in functional connectivity (FC) between patients with subcortical ischemic vascular disease (SIVD) and Alzheimer's disease (AD), especially in relation to apathy. Therefore, the aim of...
5.
Tu M, Chung H, Hsu Y, Yang J, Wu W
J Alzheimers Dis . 2022 Feb; 86(2):729-739. PMID: 35124651
Background: Alzheimer's disease (AD) and subcortical ischemic vascular disease (SIVD) have both been associated with white matter hyperintensities (WMHs) and altered cerebral blood flow (CBF) although the etiology of AD...
6.
Hsu Y, Huang S, Lin S, Yang J, Tu M, Kuo L
J Alzheimers Dis . 2022 Feb; 86(2):753-762. PMID: 35124645
Background: Prospective memory (PM), the ability to execute a previously formed intention given the proper circumstance, has been proven to be vulnerable to Alzheimer's disease. Previous studies have indicated the...
7.
Zhuang X, Kuo L, Lin S, Yang J, Tu M, Hsu Y
Front Aging Neurosci . 2021 Sep; 13:686040. PMID: 34489671
Patients with subcortical ischemic vascular disease (SIVD) often have prominent frontal dysfunction. However, it remains unclear how SIVD affects prospective memory (PM), which strongly relies on the frontoparietal network. The...
8.
Tu M, Huang S, Hsu Y, Yang J, Lin C, Kuo L
Hum Brain Mapp . 2021 Jan; 42(7):2018-2031. PMID: 33416206
Differentiating between subcortical ischemic vascular disease (SIVD), Alzheimer's disease (AD), and normal cognition (NC) remains a challenge, and reliable neuroimaging biomarkers are needed. The current study, therefore, investigated the discriminative...
9.
Tu M, Hsu Y, Yang J, Huang W, Deng J, Lin S, et al.
Front Aging Neurosci . 2020 Sep; 12:239. PMID: 32903858
The current study compared attention profiles and functional connectivity of frontal regions in patients with early-stage subcortical ischemic vascular disease (SIVD) and Alzheimer's disease (AD). Twenty patients with SIVD, 32...
10.
Yang J, Yin J, Yang D
Neurosci Lett . 2007 Apr; 418(1):106-10. PMID: 17412510
1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU) kills tumor cells via multiple actions including alkylation and carbamoylation. Previously, we have reported that formation of S-nitrosoglutathione (GSNO) in glioma cells overexpressing inducible nitric oxide synthase (iNOS)...