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Jiping Cai

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Articles 30
Citations 189
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Recent Articles
1.
Zhang A, Wei T, Tan X, Tan C, Zhuang M, Xie T, et al.
Eur J Pharmacol . 2024 Dec; 989():177227. PMID: 39736411
Purpose: Age-related macular degeneration (AMD) is the leading cause of vision loss among the elderly individuals. Retinal pigment epithelium (RPE) ferroptosis is a significant pathogenetic component in AMD. This study...
2.
Zong T, Mu T, Tan C, Xie T, Zhuang M, Wang Y, et al.
Exp Eye Res . 2024 Sep; 248:110097. PMID: 39284505
Proliferation and transdifferentiation of the retinal pigment epithelium (RPE) are hallmarks of proliferative vitreoretinopathy (PVR); however, the critical regulators of this process remain to be elucidated. Here, we investigated the...
3.
Zhang M, Wei T, Han C, Tan C, Xie T, Cai J, et al.
Environ Pollut . 2024 Aug; 360:124764. PMID: 39154884
Cigarette smoke (CS) is an important indoor air pollutant associated with an increased risk of ocular surface disease. As the eye's outermost layer, the cornea is highly sensitive to air...
4.
Wang Y, Liu Y, Cai J, Zong T, Zhang Z, Xie T, et al.
PeerJ . 2023 Dec; 11:e16569. PMID: 38130930
Background: Thyroid-associated orbitopathy (TAO) is a disease associated with autoimmune thyroid disorders and it can lead to proptosis, diplopia, and vision-threatening compressive optic neuropathy. To comprehensively understand the molecular mechanisms...
5.
Li H, Wei T, Zhuang M, Tan C, Xie T, Cai J, et al.
Cell Death Discov . 2023 Nov; 9(1):419. PMID: 37980349
Cellular senescence is a hallmark of aging and has been linked to age-related diseases. Age-related macular degeneration (AMD), the most common aging-related retinal disease, is prospectively associated with retinal pigment...
6.
Liu Y, Xu Z, Zheng H, Yang J, Wu M, Yang Q, et al.
Life Sci . 2023 Nov; 334:122217. PMID: 37925140
Aims: Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus and one of the major causes of visual impairment and blindness in industrialized countries. The early neuro-glial perturbations,...
7.
Li D, Wei T, Cai J, Xie T, Yao Y, Zhu L
Exp Eye Res . 2023 Jun; 233:109549. PMID: 37348673
Smad ubiquitylation regulatory factor-1 (Smurf1) is one of C2-WW-HECT domain E3 ubiquitin ligases, it can regulate BMP pathway by mediating ubiquitylation degradation of Smad1/Smad5. Many functions about Smurf1 also are...
8.
Xu Z, Yang J, Zheng H, Xie T, Yang Q, Cai J, et al.
Diabetes . 2023 Apr; 72(7):1012-1027. PMID: 37083867
Diabetic retinopathy (DR) is a common complication in patients with diabetes, and proliferative DR (PDR) has become an important cause of blindness; however, the mechanisms involved have not been fully...
9.
Li Y, Li H, Shao J, Zhu L, Xie T, Cai J, et al.
Biomolecules . 2022 Dec; 12(12). PMID: 36551205
Endoplasmic reticulum (ER) and mitochondrial dysfunction play fundamental roles in the pathogenesis of diabetic retinopathy (DR). However, the interrelationship between the ER and mitochondria are poorly understood in DR. Here,...
10.
Zhan P, Cui Y, Cao Y, Bao X, Wu M, Yang Q, et al.
Cell Commun Signal . 2022 Oct; 20(1):155. PMID: 36229856
Age-related macular degeneration (AMD), a progressive chronic disease of the central retina, is a leading cause of blindness worldwide. Activated macrophages recruited to the injured eyes greatly contribute to the...