Jinyeon Shin
Overview
Explore the profile of Jinyeon Shin including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
211
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Recent Articles
1.
Kuonqui K, Campbell A, Pollack B, Shin J, Sarker A, Brown S, et al.
Front Cell Dev Biol
. 2025 Mar;
13:1527971.
PMID: 40046235
The receptor tyrosine kinase vascular endothelial growth factor (VEGF) receptor 3 (VEGFR3) is the principal transmembrane receptor responsible for sensing and coordinating cellular responses to environmental lymphangiogenic stimuli in lymphatic...
2.
Campbell A, Kuonqui K, Ashokan G, Rubin J, Shin J, Pollack B, et al.
Front Physiol
. 2024 Dec;
15:1510389.
PMID: 39691094
Secondary lymphedema is a common complication following surgical treatment of solid tumors. Although more prevalent in women due to higher breast cancer rates, men also develop lymphedema, often with more...
3.
Campbell A, Baik J, Sarker A, Brown S, Park H, Kuonqui K, et al.
J Invest Dermatol
. 2024 Jun;
145(1):85-97.e4.
PMID: 38879154
Breast cancer-related lymphedema (BCRL) is characterized by skin changes, swelling, fibrosis, and recurrent skin infections. Clinical studies have suggested that lymphedema results in skin barrier defects; however, the underlying cellular...
4.
Schulz M, Akerstrom V, Song K, Broyhill S, Li M, Lambert M, et al.
bioRxiv
. 2024 Jun;
PMID: 38826322
Rationale: TRPV4 channels are critical regulators of blood vascular function and have been shown to be dysregulated in many disease conditions in association with inflammation and tissue fibrosis. These are...
5.
Kuonqui K, Campbell A, Sarker A, Roberts A, Pollack B, Park H, et al.
Cells
. 2024 Jan;
13(1).
PMID: 38201272
Vascular endothelial growth factor (VEGF) receptor 3 (VEGFR3), a receptor tyrosine kinase encoded by the gene, plays a significant role in the morphogenesis and maintenance of lymphatic vessels. Under both...
6.
Brown S, Campbell A, Kuonqui K, Sarker A, Park H, Shin J, et al.
Curr Breast Cancer Rep
. 2023 Jun;
:1-9.
PMID: 37359311
Purpose Of Review: This review aims to summarize the current knowledge regarding the pharmacological interventions studied in both experimental and clinical trials for secondary lymphedema. Recent Findings: Lymphedema is a...
7.
Campbell A, Fei T, Baik J, Park H, Shin J, Kuonqui K, et al.
PLoS One
. 2023 May;
18(5):e0283609.
PMID: 37196005
Lymphedema is a chronic condition that commonly occur from lymphatic injury following surgical resection of solid malignancies. While many studies have centered on the molecular and immune pathways that perpetuate...
8.
Brown S, Nores G, Sarker A, Ly C, Li C, Park H, et al.
Transl Res
. 2023 Feb;
257:43-53.
PMID: 36736951
Transforming growth factor-beta 1 (TGF-β1)-mediated tissue fibrosis is an important regulator of lymphatic dysfunction in secondary lymphedema. However, TGF-β1 targeting can cause toxicity and autoimmune complications, limiting clinical utility. Angiotensin...
9.
Park H, Kataru R, Shin J, Garc A Nores G, Encarnacion E, Klang M, et al.
bioRxiv
. 2023 Jan;
PMID: 36711669
Epidermal changes are histological hallmarks of secondary lymphedema, but it is unknown if keratinocytes contribute to its pathophysiology. Using clinical lymphedema specimens and mouse models, we show that keratinocytes play...
10.
Li C, Park H, Shin J, Baik J, Mehrara B, Kataru R
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36362253
Steady-state lymphatic endothelial cells (LECs) can induce peripheral tolerance by presenting endogenous antigens on MHC class I (MHC-I) molecules. Recent evidence suggests that lymph node LECs can cross-present tumor antigens...