Jingyang Qian
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Explore the profile of Jingyang Qian including associated specialties, affiliations and a list of published articles.
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9
Citations
95
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Recent Articles
1.
Qian J, Shao X, Bao H, Fang Y, Guo W, Li C, et al.
Nat Commun
. 2025 Feb;
16(1):1693.
PMID: 39956823
Deciphering the features, structure, and functions of the cell niche in tissues remains a major challenge. Here, we present scNiche, a computational framework to identify and characterize cell niches from...
2.
Qian J, Bao H, Shao X, Fang Y, Liao J, Chen Z, et al.
Nat Commun
. 2024 Jun;
15(1):5021.
PMID: 38866768
A pressing challenge in spatially resolved transcriptomics (SRT) is to benchmark the computational methods. A widely-used approach involves utilizing simulated data. However, biases exist in terms of the currently available...
3.
Yang P, Jin L, Liao J, Jin K, Shao X, Li C, et al.
Cell Genom
. 2023 Dec;
3(12):100446.
PMID: 38116121
Capturing and depicting the multimodal tissue information of tissues at the spatial scale remains a significant challenge owing to technical limitations in single-cell multi-omics and spatial transcriptomics sequencing. Here, we...
4.
Yu L, Yan J, Zhan Y, Li A, Zhu L, Qian J, et al.
J Pharm Anal
. 2023 Sep;
13(8):926-941.
PMID: 37719199
Gaining a better understanding of autoprotection against drug-induced liver injury (DILI) may provide new strategies for its prevention and therapy. However, little is known about the underlying mechanisms of this...
5.
Guo W, Hu Y, Qian J, Zhu L, Cheng J, Liao J, et al.
J Genet Genomics
. 2023 Aug;
50(9):641-651.
PMID: 37544594
Spatial omics technologies have become powerful methods to provide valuable insights into cells and tissues within a complex context, significantly enhancing our understanding of the intricate and multifaceted biological system....
6.
Qian J, Liao J, Liu Z, Chi Y, Fang Y, Zheng Y, et al.
Nat Commun
. 2023 Apr;
14(1):2484.
PMID: 37120608
Tissues are highly complicated with spatial heterogeneity in gene expression. However, the cutting-edge single-cell RNA-seq technology eliminates the spatial information of individual cells, which contributes to the characterization of cell...
7.
Liao J, Qian J, Fang Y, Chen Z, Zhuang X, Zhang N, et al.
Nat Commun
. 2022 Oct;
13(1):6498.
PMID: 36310179
Uncovering the tissue molecular architecture at single-cell resolution could help better understand organisms' biological and pathological processes. However, bulk RNA-seq can only measure gene expression in cell mixtures, without revealing...
8.
Shao X, Li C, Yang H, Lu X, Liao J, Qian J, et al.
Nat Commun
. 2022 Jul;
13(1):4429.
PMID: 35908020
Spatially resolved transcriptomics provides genetic information in space toward elucidation of the spatial architecture in intact organs and the spatially resolved cell-cell communications mediating tissue homeostasis, development, and disease. To...
9.
Li A, Yang J, Qian J, Shao X, Liao J, Lu X, et al.
Comput Struct Biotechnol J
. 2022 Jul;
20:3545-3555.
PMID: 35811838
COVID-19 has caused severe threats to lives and damage to property worldwide. The immunopathology of the disease is of particular concern. Currently, researchers have used gene co-expression networks (GCNs) to...
10.
Shao L, Liao J, Qian J, Chen W, Fan X
BMC Microbiol
. 2021 Oct;
21(1):263.
PMID: 34592929
Background: Microbiome big data from population-scale cohorts holds the key to unleash the power of microbiomes to overcome critical challenges in disease control, treatment and precision medicine. However, variations introduced...