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Jingkun Bai

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Articles 32
Citations 155
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Recent Articles
1.
Ma J, Yang H, Tian X, Meng F, Zhai X, Li A, et al.
Bioeng Transl Med . 2024 Nov; 9(6):e10702. PMID: 39545088
Conventional chemotherapeutic agents are limited by their lack of targeting and penetration and their short retention time, and chemotherapy might induce an immune suppressive environment. Peptide self-assembly can result in...
2.
Guo X, Yu J, Ma L, Yuan J, Guo T, Ma Y, et al.
RSC Adv . 2024 Sep; 14(41):30077-30083. PMID: 39315022
Herein, covalent organic polyrotaxanes (COPRs) were integrated with supermolecule self-assembly and dynamic imine bond formation to act as absorbents that captured radioactive iodine from water. The aromatic building blocks were...
3.
Gong Z, Zhao H, Bai J
Colloids Surf B Biointerfaces . 2024 May; 239:113954. PMID: 38744076
The efficacy of chemotherapeutic drugs in tumor treatment is limited by their toxicity and side effects due to their inability to selectively accumulate in tumor tissue. In addition, chemotherapeutic agents...
4.
Liu Y, Sun X, Wei C, Guo S, Song C, Zhang J, et al.
Comb Chem High Throughput Screen . 2024 Apr; PMID: 38676501
Chemotherapy resistance is a common cause of tumor treatment failure. Various molecular responses, such as increased expression of efflux transporter proteins, including Pglycoprotein (P-gp), changes in the tumor microenvironment (TME),...
5.
Xu Y, Niu C, Liang S, Guo J, Li K, Zhang J, et al.
Int J Biol Macromol . 2024 Apr; 267(Pt 2):131656. PMID: 38636749
The gut microbiota plays a significant role in the pathogenesis and remission of inflammatory bowel disease. However, conventional antibiotic therapies may alter microbial ecology and lead to dysbiosis of the...
6.
Li H, Zhang P, Yuan X, Peng S, Yang X, Li Y, et al.
Biomater Adv . 2024 Apr; 160:213852. PMID: 38636118
Immunotherapy is an emerging approach for the treatment of solid tumors. Although chemotherapy is generally considered immunosuppressive, specific chemotherapeutic agents can induce tumor immunity. In this study, we developed a...
7.
Yuan X, Liu X, Li H, Peng S, Huang H, Yu Z, et al.
Adv Healthc Mater . 2024 Apr; 13(18):e2400031. PMID: 38588449
Increasing the penetration and accumulation of antitumor drugs at the tumor site are crucial in chemotherapy. Smaller drug-loaded nanoparticles (NPs) typically exhibit increased tumor penetration and more effective permeation through...
8.
Lu D, Wang W, Li X, Wang L, Guo Y, Zhu C, et al.
Int J Biol Macromol . 2024 Apr; 266(Pt 2):131283. PMID: 38561119
Glycosaminoglycan (GAG) lyases are important tools for investigating the structure of GAGs and preparing low-molecular-weight GAGs. The PL35 family, a recently established polysaccharide lyase family, should be further investigated. In...
9.
Zhai X, Peng S, Zhai C, Wang S, Xie M, Guo S, et al.
Curr Pharm Des . 2024 Mar; 30(15):1136-1148. PMID: 38551047
Tumor metastasis is a complex process that is controlled at the molecular level by numerous cytokines. Primary breast and prostate tumors most commonly metastasize to bone, and the development of...
10.
Li H, Huang H, Tan H, Jia Q, Song W, Zhang Q, et al.
Mol Biol Rep . 2024 Jan; 51(1):197. PMID: 38270746
Cancer metastasis is the leading cause of cancer-related death. Metastasis occurs at all stages of tumor development, with unexplored changes occurring at the primary site and distant colonization sites. The...