Jinghan Lin
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Explore the profile of Jinghan Lin including associated specialties, affiliations and a list of published articles.
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21
Citations
129
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Recent Articles
1.
Zhu Y, Yao Z, Li S, Ma J, Wei C, Yu D, et al.
bioRxiv
. 2025 Feb;
PMID: 39975373
Hydrogel materials have emerged as versatile platforms for various biomedical applications. Notably, the engineered nanofiber-hydrogel composite (NHC) has proven effective in mimicking the soft tissue extracellular matrix, facilitating substantial recruitment...
2.
Hu Y, Tzeng S, Cheng L, Lin J, Villabona-Rueda A, Yu S, et al.
Proc Natl Acad Sci U S A
. 2024 Aug;
121(35):e2400194121.
PMID: 39172792
Size-dependent phagocytosis is a well-characterized phenomenon in monocytes and macrophages. However, this size effect for preferential gene delivery to these important cell targets has not been fully exploited because commonly...
3.
Li S, Hu Y, Lin J, Schneiderman Z, Shao F, Wei L, et al.
ACS Nano
. 2024 Jun;
18(24):15729-15743.
PMID: 38839059
Lipid nanoparticles (LNP) have emerged as pivotal delivery vehicles for RNA therapeutics. Previous research and development usually assumed that LNPs are homogeneous in population, loading density, and composition. Such perspectives...
4.
Wang T, Liao H, Lin J, Zhang M, Chen B, Yin R, et al.
Phytomedicine
. 2024 Apr;
129:155575.
PMID: 38636179
Background: The prevalence and incidence of type 2 diabetes mellitus (T2DM) have dramatically increased. The intestinal flora and its derived metabolites are demonstrated to play vital roles in the etiology...
5.
Hu Y, Eder B, Lin J, Li S, Zhu Y, Wang T, et al.
Mol Ther Methods Clin Dev
. 2024 Feb;
32(1):101194.
PMID: 38352269
The transfection efficiency and stability of the delivery vehicles of plasmid DNA (pDNA) are critical metrics to ensure high-quality and high-yield production of viral vectors. We previously identified that the...
6.
Zhu Y, Ma J, Shen R, Lin J, Li S, Lu X, et al.
Nat Biomed Eng
. 2023 Dec;
8(5):544-560.
PMID: 38082180
Lipid nanoparticles (LNPs) can be designed to potentiate cancer immunotherapy by promoting their uptake by antigen-presenting cells, stimulating the maturation of these cells and modulating the activity of adjuvants. Here...
7.
Qi B, Tan J, Sun Y, Cao M, Lin J, Zhang Q, et al.
ACS Chem Neurosci
. 2023 Mar;
PMID: 37000128
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts, and it is neuropathologically defined as the accumulation of abnormally hyperphosphorylated tau (p-tau). Early detection...
8.
Li D, Zhang X, Liu R, Long M, Zhou S, Lin J, et al.
Neurotoxicology
. 2023 Jan;
95:94-106.
PMID: 36669621
Objective: To explore the relationship between the proinflammatory factor high-mobility group box 1 (HMGB1) and glutamatergic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in the development of epilepsy. Methods: Thalamic reticular nucleus (TRN)...
9.
Lin J, Liu C, Xu J, Li S, Dai D, Zhang L, et al.
Biochem Biophys Res Commun
. 2022 Sep;
630:133-142.
PMID: 36155059
The phenotypic transformation of vascular smooth muscle cells (VSMCs) plays a key role in the pathological process of atherosclerosis (AS), and TRPM7 is involved in this process. In this study,...
10.
Li S, Hu Y, Li A, Lin J, Hsieh K, Schneiderman Z, et al.
Nat Commun
. 2022 Sep;
13(1):5561.
PMID: 36151112
Lipid nanoparticles (LNPs) are effective vehicles to deliver mRNA vaccines and therapeutics. It has been challenging to assess mRNA packaging characteristics in LNPs, including payload distribution and capacity, which are...