Jing-Jie Tang
Overview
Explore the profile of Jing-Jie Tang including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
615
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0
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Recent Articles
1.
Jiang S, Yang X, Yang Z, Li J, Xu M, Qu Y, et al.
Hepatology
. 2022 Feb;
76(5):1466-1481.
PMID: 35102596
Background And Aims: NASH is associated with high levels of cholesterol and triglyceride (TG) in the liver; however, there is still no approved pharmacological therapy. Synthesis of cholesterol and TG...
2.
Tang J, Li J, Qi W, Qiu W, Li P, Li B, et al.
Cell Metab
. 2021 Jan;
33(1):222.
PMID: 33406401
No abstract available.
3.
Lian J, Gao Y, Tang J, Chen X, Liu Y, Wu D, et al.
Asian J Androl
. 2020 Sep;
23(2):222-223.
PMID: 32896838
No abstract available.
4.
Jiang S, Tang J, Xiao X, Qi W, Wu S, Jiang C, et al.
PLoS Genet
. 2019 Jul;
15(7):e1008289.
PMID: 31323021
Schnyder corneal dystrophy (SCD) is a rare genetic eye disease characterized by corneal opacification resulted from deposition of excess free cholesterol. UbiA prenyltransferase domain-containing protein-1 (UBIAD1) is an enzyme catalyzing...
5.
Lu M, Zhu W, Wang X, Tang J, Zhang K, Yu G, et al.
Cell Metab
. 2019 Jan;
29(4):886-900.e5.
PMID: 30661930
Metabolic reprogramming plays an important role in supporting tumor growth. However, little is known about the metabolic alterations that promote cancer metastasis. In this study, we identify acyl-CoA thioesterase 12...
6.
Jiang S, Li H, Tang J, Wang J, Luo J, Liu B, et al.
Nat Commun
. 2018 Dec;
9(1):5138.
PMID: 30510211
Statins are inhibitors of HMG-CoA reductase, the rate-limiting enzyme of cholesterol biosynthesis, and have been clinically used to treat cardiovascular disease. However, a paradoxical increase of reductase protein following statin...
7.
Xiao X, Tang J, Peng C, Wang Y, Fu L, Qiu Z, et al.
Mol Cell
. 2017 Mar;
66(1):154-162.e10.
PMID: 28344083
Hedgehog (Hh) has been known as the only cholesterol-modified morphogen playing pivotal roles in development and tumorigenesis. A major unsolved question is how Hh signaling regulates the activity of Smoothened...
8.
Xiang Y, Tang J, Tao W, Cao X, Song B, Zhong J
J Virol
. 2015 Apr;
89(13):6805-16.
PMID: 25903345
Unlabelled: Hepatitis C virus (HCV), a single-stranded positive-sense RNA virus of the Flaviviridae family, causes chronic liver diseases, including hepatitis, cirrhosis, and cancer. HCV infection is critically dependent on host...
9.
Jiang W, Tang J, Miao H, Qu Y, Qin J, Xu J, et al.
PLoS One
. 2014 Nov;
9(11):e112632.
PMID: 25426949
Somatic cell genetics is a powerful approach for unraveling the regulatory mechanism of cholesterol metabolism. However, it is difficult to identify the mutant gene(s) due to cells are usually mutagenized...
10.
Liu T, Tang J, Li P, Shen Y, Li J, Miao H, et al.
Cell Metab
. 2012 Aug;
16(2):213-25.
PMID: 22863805
gp78 is a membrane-anchored ubiquitin ligase mediating the degradation of HMG-CoA reductase (HMGCR) and Insig-1. As a rate-limiting enzyme in cholesterol biosynthesis, HMGCR undergoes rapid sterol-promoted degradation. In contrast, destruction...