Jin-Hyeob Ryu
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Explore the profile of Jin-Hyeob Ryu including associated specialties, affiliations and a list of published articles.
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15
Citations
149
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Recent Articles
1.
Lim Y, Ryu I, Jung Y, Helmlinger G, Kim I, Park H, et al.
Mol Ther Nucleic Acids
. 2024 Oct;
35(4):102340.
PMID: 39411247
l-Type amino acid transporter 1 (LAT1)-specific ligands and polyion complexes are used as brain-specific targets to deliver RNA-based drugs across the blood-brain barrier. We characterized an LAT1-targeting antisense oligonucleotide (ASO)-encapsulated...
2.
Hwang G, Kwon M, Seo D, Kim D, Lee D, Lee K, et al.
Mol Ther Nucleic Acids
. 2024 May;
35(2):102186.
PMID: 38706632
Recent studies have highlighted the effectiveness of using antisense oligonucleotides (ASOs) for cellular RNA regulation, including targets that are considered undruggable; however, manually designing optimal ASO sequences can be labor...
3.
Ryu I, Kim D, Ro J, Park B, Kim S, Im J, et al.
Clin Biochem
. 2023 Jun;
118:110603.
PMID: 37355215
Objectives: Alzheimer's disease (AD) is an irreversible neurodegenerative disease characterized by progressive long-term memory loss and cognitive dysfunction. Neuroimaging tests for abnormal amyloid-β (Aβ) deposition are considered the most reliable...
4.
Ryu I, Kim D, Cho H, Ryu J
Rev Neurosci
. 2022 Jul;
34(1):49-62.
PMID: 35793556
Neurodegenerative diseases (NDDs) are age-related disorders characterized by progressive neurodegeneration and neuronal cell loss in the central nervous system. Neuropathological conditions such as the accumulation of misfolded proteins can cause...
5.
Koh H, Lee S, Lee H, Min J, Iwatsubo T, Teunissen C, et al.
Int J Mol Sci
. 2022 Apr;
23(7).
PMID: 35409430
The authors wish to make the following corrections to this paper [...].
6.
Koh H, Lee S, Lee H, Min J, Iwatsubo T, Teunissen C, et al.
Int J Mol Sci
. 2021 Dec;
22(23).
PMID: 34884940
Alzheimer's disease (AD) is a form of dementia characterized by progressive memory decline and cognitive dysfunction. With only one FDA-approved therapy, effective treatment strategies for AD are urgently needed. In...
7.
Lee C, Ryu I, Ryu J, Cho H
Int J Mol Sci
. 2021 Dec;
22(23).
PMID: 34884818
Alzheimer's disease (AD), an age-dependent, progressive neurodegenerative disorder, is the most common type of dementia, accounting for 50-70% of all dementia cases. Due to the increasing incidence and corresponding socioeconomic...
8.
Lee S, Cho H, Ryu J
ASN Neuro
. 2021 Oct;
13:17590914211051908.
PMID: 34668411
The innate immune system plays key roles in controlling Alzheimer's disease (AD), while secreting cytokines to eliminate pathogens and regulating brain homeostasis. Recent research in the field of AD has...
9.
Lee S, Ryu J
Front Immunol
. 2021 Sep;
12:710647.
PMID: 34531860
The innate immune system represents the first line of defense against influenza viruses, which cause severe inflammation of the respiratory tract and are responsible for more than 650,000 deaths annually...
10.
Min J, Lee J, Mun H, Kim D, Park B, Yoon B, et al.
Genes Genomics
. 2020 Nov;
42(12):1467-1475.
PMID: 33180258
Background: Diagnosis of current Alzheimer's disease (AD) is difficult even for medical specialists, and there is no clear biomarker. Also, aging is highly related to the onset of AD. Objectives:...