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Jimmy Z Liu

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Articles 34
Citations 4938
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Recent Articles
11.
Alberts R, de Vries E, Goode E, Jiang X, Sampaziotis F, Rombouts K, et al.
Gut . 2017 Aug; 67(8):1517-1524. PMID: 28779025
Objective: Primary sclerosing cholangitis (PSC) is a genetically complex, inflammatory bile duct disease of largely unknown aetiology often leading to liver transplantation or death. Little is known about the genetic...
12.
Liu J, Erlich Y, Pickrell J
Nat Genet . 2017 Jan; 49(3):325-331. PMID: 28092683
Collecting cases for case-control genetic association studies can be time-consuming and expensive. In some situations (such as studies of late-onset or rapidly lethal diseases), it may be more practical to...
13.
Ji S, Juran B, Mucha S, Folseraas T, Jostins L, Melum E, et al.
Nat Genet . 2016 Dec; 49(2):269-273. PMID: 27992413
Primary sclerosing cholangitis (PSC) is a rare progressive disorder leading to bile duct destruction; ∼75% of patients have comorbid inflammatory bowel disease (IBD). We undertook the largest genome-wide association study...
14.
Okbay A, Baselmans B, De Neve J, Turley P, Nivard M, Fontana M, et al.
Nat Genet . 2016 Nov; 48(12):1591. PMID: 27898078
No abstract available.
15.
Pickrell J, Berisa T, Liu J, Segurel L, Tung J, Hinds D
Nat Genet . 2016 Sep; 48(10):1296. PMID: 27681293
No abstract available.
16.
Okbay A, Baselmans B, De Neve J, Turley P, Nivard M, Fontana M, et al.
Nat Genet . 2016 Jul; 48(8):970. PMID: 27463399
No abstract available.
17.
Pickrell J, Berisa T, Liu J, Segurel L, Tung J, Hinds D
Nat Genet . 2016 May; 48(7):709-17. PMID: 27182965
We performed a scan for genetic variants associated with multiple phenotypes by comparing large genome-wide association studies (GWAS) of 42 traits or diseases. We identified 341 loci (at a false...
18.
Okbay A, Baselmans B, De Neve J, Turley P, Nivard M, Fontana M, et al.
Nat Genet . 2016 Apr; 48(6):624-33. PMID: 27089181
Very few genetic variants have been associated with depression and neuroticism, likely because of limitations on sample size in previous studies. Subjective well-being, a phenotype that is genetically correlated with...
19.
Liu J, van Sommeren S, Huang H, Ng S, Alberts R, Takahashi A, et al.
Nat Genet . 2015 Jul; 47(9):979-986. PMID: 26192919
Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease (IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or Immunochip genotype...
20.
Curtis J, Luo Y, Zenner H, Cuchet-Lourenco D, Wu C, Lo K, et al.
Nat Genet . 2015 Mar; 47(5):523-527. PMID: 25774636
Human genetic factors predispose to tuberculosis (TB). We studied 7.6 million genetic variants in 5,530 people with pulmonary TB and in 5,607 healthy controls. In the combined analysis of these...