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Jim Manos

Explore the profile of Jim Manos including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 784
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Recent Articles
1.
Gao M, Manos J, Whiteley G, Zablotska-Manos I
J Infect Dis . 2024 Apr; 230(3):e508-e517. PMID: 38680027
Background: Bacterial vaginosis (BV) is difficult to eradicate due to BV biofilms protecting BV bacteria (Gardnerella, Prevotella, and other genera). With the growing understanding of biofilms, we systematically reviewed the...
2.
Limantoro C, Das T, He M, Dirin D, Manos J, Kovalenko M, et al.
ACS Mater Au . 2023 Dec; 3(4):310-320. PMID: 38090131
Antibiotic resistance continues to be an ongoing problem in global public health despite interventions to reduce antibiotic overuse. Furthermore, it threatens to undo the achievements and progress of modern medicine....
3.
Manoharan A, Farrell J, Aldilla V, Whiteley G, Kriel E, Glasbey T, et al.
Front Cell Infect Microbiol . 2023 Nov; 13:1216798. PMID: 37965267
Introduction: is a key pathobiont in catheter-associated urinary tract infections (CA-UTIs), which is well known to form crystalline biofilms that occlude catheters. Urease activity alkylates urine through the release of...
4.
Aiyer A, Das T, Whiteley G, Glasbey T, Kriel F, Farrell J, et al.
Biomedicines . 2022 Nov; 10(11). PMID: 36359406
Cystic fibrosis (CF) is a disorder causing dysfunctional ion transport resulting in the accumulation of viscous mucus. This environment fosters a chronic bacterial biofilm-associated infection in the airways. , a...
5.
Aiyer A, Manos J
Microorganisms . 2022 Jul; 10(7). PMID: 35888988
In cystic fibrosis (CF), mutations in the CF transmembrane conductance regulator protein reduce ionic exchange in the lung, resulting in thicker mucus, which impairs mucociliary function, airway inflammation and infection....
6.
Manos J
APMIS . 2022 Apr; 130(12):690-705. PMID: 35393656
This narrative review seeks to examine the relationships between bacterial microbiomes and infectious disease. This is achieved by detailing how different human host microbiomes develop and function, from the earliest...
7.
Das T, Sabir S, Chen R, Farrell J, Kriel F, Whiteley G, et al.
Molecules . 2022 Feb; 27(4). PMID: 35208954
Quorum-sensing (QS) systems of  are involved in the control of biofilm formation and virulence factor production. The current study evaluated the ability of halogenated and a non-halogenated version (4d) to...
8.
Aiyer A, Visser S, Bye P, Britton W, Whiteley G, Glasbey T, et al.
Antibiotics (Basel) . 2021 Oct; 10(10). PMID: 34680757
Cystic fibrosis (CF) is a genetic disorder causing dysfunctional ion transport resulting in accumulation of viscous mucus that fosters chronic bacterial biofilm-associated infection in the airways. and are increasingly prevalent...
9.
Manos J
Microorganisms . 2021 Sep; 9(9). PMID: 34576767
The ultimate aim of any antimicrobial treatment is a better infection outcome for the patient. Here, we review the current state of treatment for bacterial infections in cystic fibrosis (CF)...
10.
Manoharan A, Ognenovska S, Paino D, Whiteley G, Glasbey T, Kriel F, et al.
Antibiotics (Basel) . 2021 Aug; 10(8). PMID: 34438950
Urinary tract infections (UTIs) affect more than 150 million individuals annually. A strong correlation exists between bladder epithelia invasion by uropathogenic bacteria and patients with recurrent UTIs. Intracellular bacteria often...