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Jihyun Shim

Explore the profile of Jihyun Shim including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 2363
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Recent Articles
1.
Choi S, Shim J, Kang P, Choi S
Org Biomol Chem . 2021 Dec; 20(3):613-618. PMID: 34951620
The α/β-peptide 11/9-helix and the β-peptide 12/10-helix belong to "mixed" helices, in which two types of hydrogen bonds with opposite directionality alternate along the helical axis. -2-Aminocyclohexanecarboxylic acid (-ACHC) is...
2.
Lee J, Shim J, Kang P, Choi M, Choi S
Org Biomol Chem . 2017 Dec; 16(3):433-438. PMID: 29264605
The 11/9-helix is among the most stable and non-traditional helical structures for α/β-peptides with alternating residue types. The effect of side chain groups of α-residues and β-residues on the 11/9-helix...
3.
Joung J, Jang M, Shim J, Ko Y, Shin S
J Korean Acad Nurs . 2017 Mar; 47(1):49-59. PMID: 28262654
Purpose: The purpose of this study was to identify non-psychiatric nurses' difficulties in caring for patients with mental illness. Methods: Data were collected from eighteen general medical-surgical nurses working at...
4.
Shim J, Shin Y, Lee I, Kim S
Adv Biochem Eng Biotechnol . 2016 Nov; 159:153-177. PMID: 27872967
L-Methionine has been used in various industrial applications such as the production of feed and food additives and has been used as a raw material for medical supplies and drugs....
5.
Lee M, Shim J, Kang P, Choi M, Choi S
Chem Commun (Camb) . 2016 Apr; 52(35):5950-2. PMID: 27056400
α/β-Peptides with alternating α-amino acid and cis-2-aminocyclohexanecarboxylic acid (cis-ACHC) residues adopt 11/9-helical conformations, the folding propensity of which decreases as the solvent polarity increases. We report a new cis-ACHC analogue,...
6.
Lopes P, Huang J, Shim J, Luo Y, Li H, Roux B, et al.
J Chem Theory Comput . 2014 Jan; 9(12):5430-5449. PMID: 24459460
Presented is a polarizable force field based on a classical Drude oscillator framework, currently implemented in the programs CHARMM and NAMD, for modeling and molecular dynamics (MD) simulation studies of...
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Shim J, Coop A, MacKerell Jr A
J Phys Chem B . 2013 Jun; 117(26):7907-17. PMID: 23758404
Molecular details of μ opioid receptor activations were obtained using molecular dynamics simulations of the receptor in the presence of three agonists, three antagonists, and a partial agonist and on...
9.
Healy J, Bezawada P, Shim J, Jones J, Kane M, MacKerell Jr A, et al.
ACS Chem Neurosci . 2013 May; 4(9):1256-66. PMID: 23713721
Opioid narcotics are used for the treatment of moderate-to-severe pain and primarily exert their analgesic effects through μ receptors. Although traditional μ agonists can cause undesired side effects, including tolerance,...
10.
Best R, Zhu X, Shim J, Lopes P, Mittal J, Feig M, et al.
J Chem Theory Comput . 2013 Jan; 8(9):3257-3273. PMID: 23341755
While the quality of the current CHARMM22/CMAP additive force field for proteins has been demonstrated in a large number of applications, limitations in the model with respect to the equilibrium...