Jihoon Ha
Overview
Explore the profile of Jihoon Ha including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
122
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Recent Articles
1.
Ha J, Kim M, Park J, Lee Y, Lee J, Shin J, et al.
Cell Rep
. 2024 Feb;
43(2):113752.
PMID: 38341852
We here demonstrate that SERTAD1 is an adaptor protein responsible for the regulation of lysine 63 (K63)-linked NLRP3 polyubiquitination by the Cullin1 E3 ubiquitin ligase upon inflammasome activation. SERTAD1 specifically...
2.
Lee J, Ha J, Kim J, Seo D, Kim M, Lee Y, et al.
Exp Mol Med
. 2023 May;
55(6):1218-1231.
PMID: 37258579
The signaling pathways governing acetaminophen (APAP)-induced liver injury have been extensively studied. However, little is known about the ubiquitin-modifying enzymes needed for the regulation of APAP-induced liver injury. Here, we...
3.
Ha J, Kim M, Seo D, Park J, Lee J, Lee J, et al.
Int J Mol Sci
. 2020 May;
21(9).
PMID: 32354117
p62/sequestosome-1 is a scaffolding protein involved in diverse cellular processes such as autophagy, oxidative stress, cell survival and death. It has been identified to interact with atypical protein kinase Cs...
4.
Seo D, Jung S, Park J, Lee J, Ha J, Kim M, et al.
EBioMedicine
. 2019 Nov;
49:55-71.
PMID: 31685442
Background: Although bone morphogenetic protein 6 (BMP6) signaling pathway has been implicated in many types of cancer, its role of tumorigenesis seems to be controversial and its ubiquitin-modifying mechanisms have...
5.
Kim J, Seo D, Kim S, Choi D, Park J, Ha J, et al.
EMBO Rep
. 2018 Mar;
19(4).
PMID: 29487085
Autophagy begins with the formation of autophagosomes, a process that depends on the activity of the serine/threonine kinase ULK1 (hATG1). Although earlier studies indicated that ULK1 activity is regulated by...
6.
Lee J, Jung S, Yang K, Bae E, Ahn S, Park J, et al.
Nat Cell Biol
. 2017 Sep;
19(10):1260-1273.
PMID: 28892081
Although the ubiquitin-editing enzyme A20 is a key player in inflammation and autoimmunity, its role in cancer metastasis remains unknown. Here we show that A20 monoubiquitylates Snail1 at three lysine...