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Jih-Jung Chen

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Articles 191
Citations 1208
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Recent Articles
1.
Tsai C, Liou Y, Li S, Liao H, Chen J
Antioxidants (Basel) . 2025 Jan; 14(1). PMID: 39857342
is a creeping evergreen shrub endemic to Taiwan. In traditional medicine, Rhamnaceae plants are used as herbal remedies for conditions such as itching, difficulty urinating, and constipation. This study explores...
2.
Liao H, Chen C, Kao Y, Liu F, Tseng C, Chen J
Chem Biol Interact . 2024 Dec; 407():111357. PMID: 39701489
Neutrophils that are overactivated can cause inflammatory diseases. Neutrophils possess various surface receptors, including G-protein-coupled chemoattractant receptors, which assist in recognizing pathogen attacks and the inflammatory environment. Therefore, targeting G-protein-coupled...
3.
Wu T, Chu Y, Chang C, Hsieh Y, Tang M, Hsu P, et al.
ChemMedChem . 2024 Sep; 19(24):e202400313. PMID: 39261284
Flavonol-metal complexes can enhance the biological activity of flavonols. Inspired by the potential of ruthenium-based drugs in pharmaceutical applications, seven flavonol-Ru (II) complexes were synthesized to evaluate their biological activities....
4.
Liang J, Cho S, Shih T, Chen J
RSC Adv . 2024 Sep; 14(39):28659-28668. PMID: 39252995
Twenty-six quinoxalin derivatives were synthesized to assess their biological activities against human non-small-cell lung cancer cells (A549 cells). Compound 4b (IC = 11.98 ± 2.59 μM) and compound 4m (IC...
5.
Liao Y, Yeh C, Chueh Y, Huang M, Wu J, Wen Y, et al.
Phytomedicine . 2024 Sep; 134:155986. PMID: 39232285
Background: Dengue, caused by the dengue virus (Orthoflavivirus dengue, encompassing DENV types 1-4), is a member of the Flaviviridae family. The symptoms of dengue range from subclinical or mild manifestations...
6.
Hsieh Y, Chuang W, Lee M, Fan Y, Huang N, Chen J
Antioxidants (Basel) . 2024 Aug; 13(8). PMID: 39199164
is a perennial herb, and its stems are high-grade tea and nourishing medicinal materials. Various solvent extracts of were evaluated for their anti-inflammatory, anti-acetylcholinesterase (AChE), antioxidant, and anti-α-glucosidase properties. Acetone...
7.
Yu C, Huang K, Chen J, Lai C, Chen G, Huang C, et al.
Free Radic Biol Med . 2024 Jul; 222:456-466. PMID: 38950659
Hepatocellular carcinoma (HCC), the primary form of liver cancer, is the third leading cause of cancer-related death globally. Hernandonine is a natural alkaloid derived from Hernandia nymphaeifolia that has been...
8.
Do H, Chen Y, Chien S, Chen Y, Zhang M, Tsou L, et al.
RSC Adv . 2024 May; 14(24):17195-17201. PMID: 38808247
The chemical screening of an octocoral identifed as has led to the isolation of five chlorinated briarane-type diterpenoids, including three known metabolites, gemmacolide X (1), frajunolide I (2), and fragilide...
9.
Hsieh Y, Hsu P, Hu A, Cheng Y, Shih T, Chen J
Molecules . 2024 May; 29(9). PMID: 38731532
A series of flavanols were synthesized to assess their biological activity against human non-small cell lung cancer cells (A549). Among the sixteen synthesized compounds, it was observed that compounds (3.14...
10.
Yu C, Lai Y, Chen J, Lee J, Chou T, Huang C, et al.
J Food Drug Anal . 2024 Mar; 31(4):696-710. PMID: 38526828
Hepatocellular carcinoma (HCC) is the most common form of liver cancer, with the second highest mortality rate in all cancer. Energy reprogramming is one of the hallmarks of cancer, and...