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Jigong Wang

Explore the profile of Jigong Wang including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 668
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Recent Articles
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Pariyar R, Wang J, Hammond R, Koo H, Dalley N, La J
J Pain . 2024 Sep; 25(12):104686. PMID: 39321909
Altered nociception, a key feature of nociplastic pain, often involves central sensitization. We previously found that central sensitization underlying a nociplastic pain state in female mice depends on the ongoing...
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Koo H, Wang J, Pariyar R, Hammond R, La J
Pain Rep . 2024 Sep; 9(5):e1186. PMID: 39263005
Introduction: The lateral parabrachial nucleus (LPBN), a crucial hub for integrating and modulating diverse sensory information, is known to express both D1 and D2 dopamine receptors and receive dopaminergic inputs....
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Yamamoto S, Duong A, Kim A, Hu C, Wiemers B, Wang J, et al.
Spine (Phila Pa 1976) . 2023 Mar; 48(11):E169-E176. PMID: 36940259
Study Design: Double-blinded, prospective laboratory animal study. Objective: To examine whether intraoperative spinal cord stimulation (SCS) inhibits the development of spine surgery-induced hypersensitivity. Summary Of Background Data: Managing postoperative pain...
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Wang X, Wang J, Fokina V, Patrikeeva S, Rytting E, Ahmed M, et al.
Drug Metab Pharmacokinet . 2022 Nov; 47:100477. PMID: 36368298
Although methadone is effective in the management of acute pain, the complexity of its absorption-distribution-metabolism-excretion profile limits its use as an opioid of choice for perioperative analgesia. Because deuteration is...
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McDonough K, Hammond R, Wang J, Tierney J, Hankerd K, Chung J, et al.
Brain Behav Immun . 2022 Oct; 107:215-224. PMID: 36273650
Previously we developed a murine model in which postinjury stimulation of an injured area triggers a transition to a nociplastic pain state manifesting as persistent mechanical hypersensitivity outside of the...
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Hankerd K, Koo H, McDonough K, Wang J, Pariyar R, Tang S, et al.
Pain . 2022 Aug; 164(2):402-412. PMID: 35975896
Nociplastic pain conditions develop predominantly in women. We recently established a murine nociplastic pain model by applying postinjury thermal (40°C) stimulation to an injured (capsaicin-injected) area, triggering a transition to...
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Wang J, Hamill O
J Integr Neurosci . 2022 Jan; 20(4):825-837. PMID: 34997707
Here we use immunohistochemistry to examine the expression of Piezo2 in neurons of the mouse dorsal root ganglia and brain. Whereas Piezo2 is expressed in the large majority (≥ 90%)...
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Kearns A, Jayasi J, Liu X, Wang J, Shi Y, Chung J, et al.
Front Synaptic Neurosci . 2021 Dec; 13:748929. PMID: 34867259
Opioids are widely used for pain relief; however, chronic opioid use causes a paradoxical state of enhanced pain sensitivity, termed "Opioid-induced hyperalgesia (OIH)." Despite the clinical importance of OIH, the...
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Hankerd K, McDonough K, Wang J, Tang S, Chung J, La J
Pain . 2021 Jul; 163(3):461-473. PMID: 34285154
Acute injury-induced pain can transition to chronic nociplastic pain, which predominantly affects women. To facilitate studies on the underlying mechanisms of nociplastic pain, we developed a mouse model in which...