Jigang Guo
Overview
Explore the profile of Jigang Guo including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
2219
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0
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Recent Articles
1.
A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche
Xiang J, Guo J, Zhang S, Wu H, Chen Y, Wang J, et al.
BMC Biol
. 2023 Aug;
21(1):169.
PMID: 37553612
Background: The nutrient-absorbing villi of small intestines are renewed and repaired by intestinal stem cells (ISCs), which reside in a well-organized crypt structure. Genetic studies have shown that Wnt molecules...
2.
Xiang J, Zhang Y, Bao D, Cao N, Zhang X, Li P, et al.
Sci Rep
. 2017 Jun;
7(1):3563.
PMID: 28620185
The gastrointestinal tract is responsible for food digestion and absorption. The muscularis propria propels the foodstuff through the GI tract and defects in intestine motility may cause obstruction disorders. Our...
3.
Wang K, Li P, Dong Y, Cai X, Hou D, Guo J, et al.
J Biol Chem
. 2011 Jan;
286(11):9468-76.
PMID: 21199864
microRNAs (miRNAs) are generally thought to negatively regulate the expression of their target genes by mRNA degradation or by translation repression. Here we show an efficient way to identify miRNA...
4.
Guo J, Dong Q, Fang Z, Chen X, Lu H, Wang K, et al.
Cancer Biol Ther
. 2010 Feb;
9(6):446-52.
PMID: 20147780
The discovery of microRNAs (miRNAs) has opened a new avenue for both diagnosis and treatment of cancers. Accumulating experimental evidences indicate that miRNAs are aberrantly expressed in different tumor types...
5.
Chen X, Wang K, Chen J, Guo J, Yin Y, Cai X, et al.
J Biol Chem
. 2008 Dec;
284(8):5362-9.
PMID: 19073597
UCP2 and UCP3, two novel uncoupling proteins, are important regulators of energy expenditure and thermogenesis in various organisms. The striking disparity between UCP2 mRNA and protein levels in muscle tissues...
6.
Chen X, Ba Y, Ma L, Cai X, Yin Y, Wang K, et al.
Cell Res
. 2008 Sep;
18(10):997-1006.
PMID: 18766170
Dysregulated expression of microRNAs (miRNAs) in various tissues has been associated with a variety of diseases, including cancers. Here we demonstrate that miRNAs are present in the serum and plasma...