Jiaxuan Cheng
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Explore the profile of Jiaxuan Cheng including associated specialties, affiliations and a list of published articles.
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15
Citations
465
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Recent Articles
1.
Zhang B, Chuang G, Biju A, Biner D, Cheng J, Wang Y, et al.
Cell Rep
. 2024 May;
43(6):114285.
PMID: 38819987
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a plasma protein that controls cholesterol homeostasis. Here, we design a human PCSK9 mimic, named HIT01, with no consecutive 9-residue stretch in common...
2.
Yang L, Qi K, Zhang P, Cheng J, Soha H, Jin Y, et al.
Bioengineering (Basel)
. 2024 May;
11(5).
PMID: 38790296
Purpose: This study aimed to employ the incremental digital image correlation (DIC) method to obtain displacement and strain field data of the cornea from Corvis ST (CVS) sequences and access...
3.
Cheng J, Yang L, Ye Y, He L, Chen S, Wang J
Bioengineering (Basel)
. 2024 Mar;
11(3).
PMID: 38534495
Keratoconus (KC), a leading cause of vision impairment, has an unclear aetiology. This study used Mendelian randomization (MR) to explore the causal links between various factors (smoking, asthma, Down syndrome,...
4.
Zhang P, Yang L, Mao Y, Zhang X, Cheng J, Miao Y, et al.
Comput Biol Med
. 2024 Mar;
172:108286.
PMID: 38493602
Purpose: To ascertain whether the integration of raw Corvis ST data with an end-to-end CNN can enhance the diagnosis of keratoconus (KC). Method: The Corvis ST is a non-contact device...
5.
In-vivo high-speed biomechanical imaging of the cornea using Corvis ST and digital image correlation
Wang B, Yang L, Cheng J, Wang J, Mei Y
Comput Biol Med
. 2023 Jan;
153:106540.
PMID: 36646022
In-vivo corneal biomechanical characterization has gained significant clinical relevance in ophthalmology, especially in the early diagnosis of eye disorders and diseases (e.g. keratoconus). In clinical medicine, the air-puff-based tonometers such...
6.
Jiang F, Shen J, Cheng J, Wang X, Yang J, Li N, et al.
Sci Adv
. 2022 Apr;
8(17):eabm2343.
PMID: 35486720
Extracellular contractile injection systems (eCISs) are widespread bacterial nanomachines that resemble T4 phage tail. As a typical eCIS, virulence cassette (PVC) was proposed to inject toxins into eukaryotic cells by...
7.
Cheng J, Li N, Huo Y, Dang S, Tye B, Gao N, et al.
Nat Commun
. 2022 Apr;
13(1):2411.
PMID: 35477717
No abstract available.
8.
Cheng J, Li N, Huo Y, Dang S, Tye B, Gao N, et al.
Nat Commun
. 2022 Mar;
13(1):1396.
PMID: 35296675
The Dbf4-dependent kinase Cdc7 (DDK) regulates DNA replication initiation by phosphorylation of the MCM double hexamer (MCM-DH) to promote helicase activation. Here, we determine a series of cryo electron microscopy...
9.
Wang X, Cheng J, Shen J, Liu L, Li N, Gao N, et al.
Sci China Life Sci
. 2021 Jun;
65(3):618-630.
PMID: 34185241
The extracellular contractile injection systems (eCISs) are encoded in the genomes of a large number of bacteria and archaea. We have previously characterized the overall structure of Photorhabdus Virulence Cassette...
10.
Yang H, Yu Z, Chen X, Li J, Li N, Cheng J, et al.
Nat Commun
. 2021 Jan;
12(1):339.
PMID: 33436626
Tuberous sclerosis complex (TSC) integrates upstream stimuli and regulates cell growth by controlling the activity of mTORC1. TSC complex functions as a GTPase-activating protein (GAP) towards small GTPase Rheb and...