Jiaoxiang Chen
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Explore the profile of Jiaoxiang Chen including associated specialties, affiliations and a list of published articles.
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28
Citations
549
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Recent Articles
1.
Chen J, Gan X, Su S, Jiao S, Gong Z, Liu Z, et al.
J Control Release
. 2025 Feb;
381:113556.
PMID: 39983927
Intervertebral disc degeneration (IVDD) is a multifaceted and complex condition primarily driven by excessive inflammation, degradation of the extracellular matrix (ECM), and dysfunction of nucleus pulposus cells (NPCs). Despite extensive...
2.
Ye H, Wu X, Shen Y, Zhao L, Zhang H, Yang J, et al.
Int Immunopharmacol
. 2024 Sep;
142(Pt A):113072.
PMID: 39241514
Background: Aberrant differentiation of Th17 cells has been identified as a critical factor in the development of rheumatoid arthritis (RA). BLIMP1 plays a key role in regulating plasma cell differentiation,...
3.
Geng Y, Lou J, Wu J, Tao Z, Yang N, Kuang J, et al.
Adv Sci (Weinh)
. 2024 Sep;
11(40):e2405759.
PMID: 39225315
A short peptide termed NEMO-binding domain (NBD) peptide has an inhibitory effect on nuclear factor kappa-B (NF-κB). Despite its efficacy in inhibiting inflammatory responses, the precise neuroprotective mechanisms of NBD...
4.
Xiang L, Lou J, Zhao J, Geng Y, Zhang J, Wu Y, et al.
Mol Neurobiol
. 2024 Jun;
62(1):626-642.
PMID: 38888836
Lysosomes play a crucial role in various intracellular pathways as their final destination. Various stressors, whether mild or severe, can induce lysosomal membrane permeabilization (LMP), resulting in the release of...
5.
Ye H, Cai T, Shen Y, Zhao L, Zhang H, Yang J, et al.
J Cell Mol Med
. 2024 Jun;
28(11):e18476.
PMID: 38842136
Osteoarthritis (OA) is a complicated disease that involves apoptosis and mitophagy. MST1 is a pro-apoptotic factor. Hence, decreasing its expression plays an anti-apoptotic effect. This study aims to investigate the...
6.
Hong H, Hu J, Xu H, Xia D, Pan X, Chen X, et al.
Spine (Phila Pa 1976)
. 2023 Oct;
49(4):221-231.
PMID: 37871182
Study Design: Cross-sectional and retrospective cohort study. Objective: We investigated the effect of 3 types of short stature [partial growth hormone deficiency (GHD), GHD, and idiopathic short stature (ISS)] and...
7.
Wang J, Xia D, Lin Y, Xu W, Wu Y, Chen J, et al.
Exp Mol Med
. 2022 Mar;
54(3):285-297.
PMID: 35332256
Low back pain, triggered by intervertebral disc degeneration (IVDD), is one of the most common causes of disability and financial expenditure worldwide. However, except for surgical interventions, effective medical treatment...
8.
Shi Y, Chen J, Li S, Wu Y, Yu C, Ni L, et al.
Phytomedicine
. 2022 Feb;
98:153928.
PMID: 35104760
Background: Osteoarthritis (OA) is a globally prevalent degenerative disease characterized by extracellular matrix (ECM) degradation and inflammation. Tangeretin is a natural flavonoid that has anti-inflammatory properties. Studies have not explored...
9.
Zhang Z, Xu T, Chen J, Shao Z, Wang K, Yan Y, et al.
Cell Death Dis
. 2021 Oct;
12(10):915.
PMID: 34620831
No abstract available.
10.
Hu S, Zhang C, Qian T, Bai Y, Chen L, Chen J, et al.
Oxid Med Cell Longev
. 2021 Jul;
2021:6694964.
PMID: 34211633
One of the causes of intervertebral disc degeneration (IVDD) is nucleus pulposus cell (NPC) death, possibly apoptosis. In this study, we explored the role of the Nrf2/Sirt3 pathway and tert-butylhydroquinone...