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Jian-Zhang Pan

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Articles 29
Citations 131
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Recent Articles
1.
Xu Q, Jiang Y, Chen J, Wu J, Chen Y, Fan Q, et al.
Adv Sci (Weinh) . 2025 Jan; e2414769. PMID: 39840604
The efficacy of cancer immunotherapy is significantly influenced by the heterogeneity of individual tumors and immune responses. To investigate this phenomenon, a microfluidic platform is constructed for profiling immune-cancer cell...
2.
Lu J, Wang H, Guo Q, Wang J, Li T, Chen K, et al.
Nat Commun . 2024 Oct; 15(1):8826. PMID: 39396057
The current throughput of conventional organic chemical synthesis is usually a few experiments for each operator per day. We develop a robotic system for ultra-high-throughput chemical synthesis, online characterization, and...
3.
Ying W, Shi S, Wang H, Chen J, Pan J, Fang Q
Anal Chem . 2024 Jul; 96(32):12991-12998. PMID: 39075986
With the increasing demand for trace sample analysis, injecting trace samples into liquid chromatography-mass spectrometry (LC-MS) systems with minimal loss has become a major challenge. Herein, we describe an in...
4.
Wu J, Xu Q, Jiang Y, Chen J, Ying W, Fan Q, et al.
Anal Chem . 2024 Mar; 96(14):5499-5508. PMID: 38547315
Characterizing the profiles of proteome and metabolome at the single-cell level is of great significance in single-cell multiomic studies. Herein, we proposed a novel strategy called one-shot single-cell proteome and...
5.
Wang Y, Guan Z, Shi S, Jiang Y, Zhang J, Yang Y, et al.
Nat Commun . 2024 Feb; 15(1):1279. PMID: 38341466
The shotgun proteomic analysis is currently the most promising single-cell protein sequencing technology, however its identification level of ~1000 proteins per cell is still insufficient for practical applications. Here, we...
6.
Jiang Y, Zhu L, Cao L, Wu Q, Chen J, Wang Y, et al.
Cell Rep . 2023 Nov; 42(11):113455. PMID: 37976159
Although single-cell multi-omics technologies are undergoing rapid development, simultaneous transcriptome and proteome analysis of a single-cell individual still faces great challenges. Here, we developed a single-cell simultaneous transcriptome and proteome...
7.
Lin T, Wang J, Shi Q, Wang H, Pan J, Fang Q
Anal Chim Acta . 2023 Jan; 1239:340698. PMID: 36628766
On-site nucleic acid testing (NAT) plays an important role for disease monitoring and pathogen diagnosis. In this work, we developed an automated and fully-integrated nucleic acid analyzer by combining the...
8.
Pan J, Fan C, Zuo Z, Yuan Y, Wang H, Dong Z, et al.
Anal Bioanal Chem . 2022 Nov; 415(1):17-25. PMID: 36334114
The continuing pursuit for a healthy life has led to the urgent need for on-site analysis. In response to the urgent needs of on-site analysis, we propose a novel concept,...
9.
Zuo Z, Pan J, Fang Q
Talanta . 2022 Jun; 249:123585. PMID: 35688079
Herein, we described an integrated microfluidic system for multi-target biochemical analysis of micro-volumes of blood samples. This system mainly consists of a microfluid handling module, an integrated microwell array chip,...
10.
Zhang M, Peng Y, Pan J, Fang X, Li H, Zhang X, et al.
Talanta . 2021 Dec; 239:123063. PMID: 34890938
In this work, a laser-induced fluorescence (LIF) detection system built in a modular assembling mode was developed based on commercial LEGO blocks and 3D printed blocks. We designed and fabricated...