Jian-Huan Chen
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Explore the profile of Jian-Huan Chen including associated specialties, affiliations and a list of published articles.
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42
Citations
283
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Recent Articles
1.
Jin Y, Guo Y, Xiong S, Zhang N, Chen J, Liu F
mSphere
. 2025 Feb;
:e0101224.
PMID: 39998235
is an important human respiratory pathogen that causes mild-to-moderate community-acquired pneumonia (MPP), particularly in children. RNA editing plays a vital role in pathogen infection and host immune response, but it...
2.
Jin Y, Liang Y, Pan J, Huang W, Feng Y, Sui W, et al.
Front Immunol
. 2024 Sep;
15:1413704.
PMID: 39308856
Background: COVID-19 vaccines are crucial for reducing the threat and burden of the pandemic on global public health, yet the epigenetic, especially RNA editing in response to the vaccines remains...
3.
Wei Z, Wang L, Gao D, Zhu L, Wu J, Shi J, et al.
Neuroscience
. 2024 Sep;
560:167-180.
PMID: 39293730
Previous studies have demonstrated the roles of both microglia homeostasis and RNA editing in sepsis-associated encephalopathy (SAE), yet their relationship remains to be elucidated. In this study, we analyzed bulk...
4.
Li Y, Liang Y, Zhang J, Li N, Wei Z, Rao Y, et al.
Front Neurosci
. 2024 Aug;
18:1435185.
PMID: 39156629
Introduction: The activation of cerebral endothelial cells (CECs) has recently been reported to be the earliest acute neuroinflammation event in the CNS during sepsis-associated encephalopathy (SAE). Importantly, adenosine-to-inosine (A-to-I) RNA...
5.
Jin Y, Liang Y, Wei Z, Sui W, Chen J
Brain Commun
. 2024 Aug;
6(4):fcae260.
PMID: 39135964
Sepsis-associated encephalopathy is a diffuse brain dysfunction secondary to infection. It has been established that factors such as age and sex can significantly contribute to the development of sepsis-associated encephalopathy....
6.
Gao J, Xia S, Hide G, Li B, Liu Y, Wei Z, et al.
NPJ Biofilms Microbiomes
. 2024 Jul;
10(1):61.
PMID: 39060267
The gut microbiota has been demonstrated to play a significant role in the pathogenesis of Parkinson's disease (PD). However, conflicting findings regarding specific microbial species have been reported, possibly due...
7.
Bao C, Feng J, Cui J, Guo T, He Y, Wei Z, et al.
Biochem Biophys Res Commun
. 2024 Jul;
726:150213.
PMID: 38964186
The F11 receptor (F11R) gene encoding junctional adhesion molecule A has been associated with gastric cancer (GC) and colorectal cancer (CRC), in which its role and regulation remain to be...
8.
Kong F, Feng J, Yao J, Lu Y, Guo T, Sun M, et al.
BMC Med
. 2024 Jun;
22(1):229.
PMID: 38853264
Background: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive ages. Our previous study has implicated a possible link between RNA editing and PCOS, yet the...
9.
Jin Y, Liang Y, Huang W, Guo L, Cheng L, Ran T, et al.
BMC Genomics
. 2024 May;
25(1):431.
PMID: 38693480
Ophthalmic manifestations have recently been observed in acute and post-acute complications of COVID-19 caused by SARS-CoV-2 infection. Our precious study has shown that host RNA editing is linked to RNA...
10.
Kong F, Huang P, Chen J, Ma Y
Reprod Sci
. 2024 Apr;
31(11):3323-3333.
PMID: 38653859
Polycystic Ovary Syndrome (PCOS) is a metabolic disorder characterized by hyperandrogenism and related symptoms in women of reproductive age. Emerging evidence suggests that chronic low-grade inflammation plays a significant role...