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Jia-Jiun Yan

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Articles 18
Citations 267
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Recent Articles
1.
Shih S, Yan J, Lu S, Chuang Y, Lin H, Chou M, et al.
Int J Mol Sci . 2023 Apr; 24(7). PMID: 37047570
The gills are the major organ for Na uptake in teleosts. It was proposed that freshwater (FW) teleosts adopt Na/H exchanger 3 (Nhe3) as the primary transporter for Na uptake...
2.
Chuang H, Chiu L, Yan J, Chang C, Tang Y, Chou M, et al.
J Hazard Mater . 2022 Dec; 445:130539. PMID: 36502720
Anthropogenic acidification of water is an on-going environmental disaster for freshwater fishes. Fishes rely on ammonia excretion to eliminate the excess acid and mitigate the harmful effects; however, it remains...
3.
Tseng Y, Yan J, Furukawa F, Chen R, Lee J, Tsou Y, et al.
Front Physiol . 2022 Oct; 13:947958. PMID: 36277196
Understanding Na uptake mechanisms in vertebrates has been a research priority since vertebrate ancestors were thought to originate from hyperosmotic marine habitats to the hypoosmotic freshwater system. Given the evolutionary...
4.
Shih S, Yan J, Tsou Y, Lu S, Wang M, Chou M, et al.
Int J Mol Sci . 2022 Apr; 23(8). PMID: 35457237
Molecular and physiological analyses in ionoregulatory organs (e.g., adult gills and embryonic skin) are essential for studying fish ion regulation. Recent progress in the molecular physiology of fish ion regulation...
5.
Shih S, Yan J, Wang Y, Tsou Y, Chiu L, Tseng Y, et al.
J Endocrinol . 2021 Sep; 251(2):149-159. PMID: 34494970
Estrogen-related receptors (ERRs) are known to function in mammalian kidney as key regulators of ion transport-related genes; however, a comprehensive understanding of the physiological functions of ERRs in vertebrate body...
6.
Yan J, Lee Y, Tsou Y, Tseng Y, Hwang P
J Endocrinol . 2020 Jul; 246(3):277-288. PMID: 32698133
Timely adjustment of osmoregulation upon acute salinity stress is essential for the survival of euryhaline fish. This rapid response is thought to be tightly controlled by hormones; however, there are...
7.
Stumpp M, Petersen I, Thoben F, Yan J, Leippe M, Hu M
J Exp Biol . 2020 Apr; 223(Pt 9). PMID: 32253289
Larval stages of members of the Abulacraria superphylum including echinoderms and hemichordates have highly alkaline midguts. To date, the reason for the evolution of such extreme pH conditions in the...
8.
Tseng Y, Yan J, Furukawa F, Hwang P
Bioessays . 2020 Mar; 42(5):e1900161. PMID: 32163625
How vertebrates evolved different traits for acid excretion to maintain body fluid pH homeostasis is largely unknown. The evolution of Na /H  exchanger (NHE)-mediated NH excretion in fishes is reported,...
9.
Lee H, Stumpp M, Yan J, Tseng Y, Heinzel S, Hu M
Comp Biochem Physiol A Mol Integr Physiol . 2019 Apr; 234:87-97. PMID: 31022521
Sea urchin larvae reduce developmental rates accompanied by changes in their energy budget when exposed to acidified conditions. The necessity to maintain highly alkaline conditions in their digestive systems led...
10.
Yan J, Hwang P
Gen Comp Endocrinol . 2019 Mar; 277:20-29. PMID: 30878350
Maintenance of internal ionic and acid-base homeostasis is critical for survival in all biological systems. Similar to mammals, aquatic fishes have developed sophisticated homeostatic mechanisms to mitigate metabolic or environmental...