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Ji-Young Kang

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Articles 37
Citations 448
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Recent Articles
1.
Kang J, Mun D, Park M, Yoo G, Kim H, Yun N, et al.
Int J Nanomedicine . 2025 Mar; 20:2575-2592. PMID: 40046817
Purpose: Small-interfering RNA (siRNA) therapy holds significant potential for treating cardiac injury; however, its clinical application is constrained by poor blood stability and insufficient cellular uptake. Extracellular vesicles (EVs) have...
2.
Mun D, Kang J, Park M, Yoo G, Kim H, Yun N, et al.
Stem Cell Res . 2024 Oct; 81:103592. PMID: 39454535
Long QT syndrome type 2 (LQT2) is a heart disorder resulting from a loss-of-function mutation in theKCNH2gene that causes loss of Kv11.1 channel function, potentially resulting in syncope, arrhythmias, and...
3.
Mun D, Yoo G, Park M, Kang J, Yun N, Joung B
Stem Cell Res . 2024 Oct; 81:103571. PMID: 39388802
Long QT syndrome type 1 (LQT1) is a rare heart disorder caused by a loss-of-function mutation in the KCNQ1 gene that causes loss of Kv7.1 channel function, which can lead...
4.
Kang J, Choi H, Oh J, Kim M, Lee D
Medicina (Kaunas) . 2024 Sep; 60(9). PMID: 39336475
: Fine particulate matter, PM, is becoming a major threat to human health, particularly in terms of respiratory diseases. Pyroptosis is a recently discovered and distinct form of cell death,...
5.
Mun D, Kang J, Kim H, Yun N, Joung B
J Control Release . 2024 May; 370:798-810. PMID: 38754633
Myocardial infarction (MI) is a major cause of morbidity and mortality worldwide. Although clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein 9 (Cas9) gene editing holds immense potential for genetic...
6.
Kang J, Mun D, Chun Y, Park D, Kim H, Yun N, et al.
J Extracell Vesicles . 2023 Oct; 12(10):e12371. PMID: 37795828
Small-interfering RNA (siRNA) therapy is considered a powerful therapeutic strategy for treating cardiac hypertrophy, an important risk factor for subsequent cardiac morbidity and mortality. However, the lack of safe and...
7.
Mun D, Kang J, Chun Y, Park D, Kim H, Yun N, et al.
Stem Cell Res . 2022 Oct; 65:102940. PMID: 36260954
PITX2 is a homeobox gene located in the human 4q25 locus and is commonly associated with atrial fibrillation (AF). Here, we generated two PITX2 knock-out human induced pluripotent stem cell...
8.
Kang J, Mun D, Chun Y, Park D, Kim H, Yun N, et al.
Stem Cell Res . 2022 Aug; 64:102901. PMID: 36037555
TTN mutations are the common genetic cause for various types of cardiomyopathies (e.g., dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy) and skeletal myopathies. Here, we generated...
9.
Kang J, Mun D, Chun Y, Kim H, Yun N, Lee S, et al.
Stem Cell Res . 2022 Aug; 63:102878. PMID: 35917600
E192K missense mutation of TPM1 has been found in different types of cardiomyopathies (e.g., hypertrophic cardiomyopathy, dilated cardiomyopathy, and left ventricular non-compaction), leading to systolic dysfunction, diastolic dysfunction, and/or tachyarrhythmias....
10.
Kang J, Mun D, Kim H, Yun N, Joung B
Heart Rhythm . 2022 Jun; 19(9):1450-1458. PMID: 35660473
Background: Exosomal long noncoding RNAs (lncRNAs) are known as ideal diagnostic biomarkers of various diseases. However, there are no reports on the use of serum exosomal lncRNAs as diagnostic biomarkers...