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Ji-Youn Youn

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Articles 16
Citations 833
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Recent Articles
1.
Zhou B, Zong N, Zhang Y, Huang Y, Youn J, Cai H
Redox Biol . 2024 Jul; 75:103178. PMID: 38986245
To this date, COVID-19 remains an unresolved pandemic, and the impairment of redox homeostasis dictates the severity of clinical outcomes. Here we examined initial UCLA cohort of 440 COVID-19 patients...
2.
Sun H, Olson K, Gao C, Prosdocimo D, Zhou M, Wang Z, et al.
Circulation . 2016 Apr; 133(21):2038-49. PMID: 27059949
Background: Although metabolic reprogramming is critical in the pathogenesis of heart failure, studies to date have focused principally on fatty acid and glucose metabolism. Contribution of amino acid metabolic regulation...
3.
Li Q, Youn J, Li S, Cai H
J Hypertens . 2015 Sep; 33(11):2368-70. PMID: 26372324
No abstract available.
4.
Youn J, Zhou J, Cai H
Mol Endocrinol . 2015 Jun; 29(8):1123-33. PMID: 26121233
We have recently shown that angiotensin II-mediated uncoupling of endothelial nitric oxide synthase (eNOS) contributes to endothelial dysfunction in streptozotocin-induced type 1 diabetes mellitus. However, it has remained unclear whether...
5.
Li Q, Youn J, Cai H
J Hypertens . 2015 Apr; 33(6):1128-36. PMID: 25882860
Reduced nitric oxide bioavailability contributes to endothelial dysfunction and hypertension. The endothelial isoform of nitric oxide synthase (eNOS) is responsible for the production of nitric oxide within the endothelium. Loss...
6.
Youn J, Siu K, Lob H, Itani H, Harrison D, Cai H
Diabetes . 2014 Feb; 63(7):2344-55. PMID: 24550188
Obesity is associated with vascular diseases that are often attributed to vascular oxidative stress. We tested the hypothesis that vascular oxidative stress could induce obesity. We previously developed mice that...
7.
Youn J, Zhang J, Zhang Y, Chen H, Liu D, Ping P, et al.
J Mol Cell Cardiol . 2013 May; 62:72-9. PMID: 23643589
Atrial fibrillation (AF) is the most common cardiac arrhythmia. Patients with AF have up to seven-fold higher risk of suffering from ischemic stroke. Better understanding of etiologies of AF and...
8.
Li J, Iorga A, Sharma S, Youn J, Partow-Navid R, Umar S, et al.
Anesthesiology . 2012 Jul; 117(4):836-46. PMID: 22814384
Background: We have recently shown that postischemic administration of intralipid protects the heart against ischemia-reperfusion injury. Here we compared the cardioprotective effects of intralipid with cyclosporine-A, a potent inhibitor of...
9.
Li J, Umar S, Iorga A, Youn J, Wang Y, Regitz-Zagrosek V, et al.
Basic Res Cardiol . 2012 Jun; 107(4):271. PMID: 22648276
Although the murine late pregnant (LP) heart is speculated to be a better functioning heart during physiological conditions, the susceptibility of LP hearts to I/R injury is still unknown. The...
10.
Youn J, Nguyen A, Cai H
Clin Sci (Lond) . 2012 May; 123(8):509-18. PMID: 22568671
Oestrogen protects cardiovascular health partially via an up-regulation of NO• (NO radical) production. Its synthetic analogue DES (diethylstilbestrol), used as a potent androgen deprivation therapy for patients with prostate cancer,...