Ji-Seon Kang
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Explore the profile of Ji-Seon Kang including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
284
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0
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Recent Articles
1.
Chang Y, Kang J, Jung K, Chung D, Ha S, Kim Y, et al.
Allergy Asthma Immunol Res
. 2022 Jan;
14(1):99-116.
PMID: 34983110
Purpose: Three observations drove this study. First, 2'-5'-oligoadenylate synthetase-like protein (OASL) is a negative regulator of type I interferon (IFN). Second, type I IFN plays a central role during virus...
2.
Kang J, Hwang Y, Kim L, Lee S, Lee W, Kim-Ha J, et al.
Mol Cells
. 2018 Feb;
41(3):214-223.
PMID: 29463066
Oligoadenylate synthetase (OAS) protein family is the major interferon (IFN)-stimulated genes responsible for the activation of RNase L pathway upon viral infection. OAS-like (OASL) is also required for inhibition of...
3.
Zhang Q, Lee W, Kang J, Kim L, Kim Y
Exp Mol Med
. 2018 Feb;
50(2):e439.
PMID: 29400702
During mycobacteria infection, anti-inflammatory responses allow the host to avoid tissue damage caused by overactivation of the immune system; however, little is known about the negative modulators that specifically control...
4.
Lee W, Yan J, Kang J, Kim L, Kim Y
Biochem Biophys Res Commun
. 2017 Oct;
493(4):1491-1497.
PMID: 28988116
Sepsis is a life-threatening condition caused by an uncontrolled response to bacterial infection. Impaired bactericidal activity in the host is directly associated with severe sepsis; however, the underlying regulatory mechanism(s)...
5.
Lee W, Yan J, Kang J, Chung S, Kim L
Microbiol Immunol
. 2017 Oct;
61(12):523-530.
PMID: 28976590
Trehalose 6,6'-dimycolate (TDM), or cord factor, is a crucial stimulus of immune responses during Mycobacterium tuberculosis infection. Although TDM has immuno-stimulatory properties, including adjuvant activity and the ability to induce...
6.
Lee W, Yan J, Kang J, Zhang Q, Choi W, Kim L, et al.
Sci Rep
. 2017 Jan;
7:41106.
PMID: 28112221
Sepsis is a systemic inflammatory response to bacterial infection. The therapeutic options for treating sepsis are limited. Impaired neutrophil recruitment into the infection site is directly associated with severe sepsis,...
7.
Lee W, Kang J, Choi W, Zhang Q, Kim C, Choi U, et al.
Nat Commun
. 2016 Apr;
7:11322.
PMID: 27089465
In response to persistent mycobacteria infection, the host induces a granuloma, which often fails to eradicate bacteria and results in tissue damage. Diverse host receptors are required to control the...
8.
Choi U, Kang J, Hwang Y, Kim Y
Exp Mol Med
. 2015 Mar;
47:e144.
PMID: 25744296
The study of antiviral pathways to reveal methods for the effective response and clearance of virus is closely related to understanding interferon (IFN) signaling and its downstream target genes, IFN-stimulated...
9.
Lee M, Kim B, Lee S, Cho W, Lee W, Kang J, et al.
Mol Cells
. 2013 May;
35(6):498-513.
PMID: 23666259
Lipopolysaccharide (LPS), the major causative agent of bacterial sepsis, has been used by many laboratories in genome-wide expression profiling of the LPS response. However, these studies have predominantly used in...
10.
Lee W, Kang J, Yan J, Lee M, Jeon B, Cho S, et al.
PLoS Pathog
. 2012 Apr;
8(4):e1002614.
PMID: 22496642
Trehalose 6,6'-dimycolate (TDM), a cord factor of Mycobacterium tuberculosis (Mtb), is an important regulator of immune responses during Mtb infections. Macrophages recognize TDM through the Mincle receptor and initiate TDM-induced...