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Jesus Galvez

Explore the profile of Jesus Galvez including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 80
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Recent Articles
1.
Pereira F, McCauley M, Lev K, Verhey-Henke L, Condren A, Harte R, et al.
Metab Eng . 2024 Nov; 88:63-76. PMID: 39581342
Plecomacrolides, such as concanamycins and bafilomycins, are potent and specific inhibitors of vacuolar-type ATPase. Concanamycins are 18-membered macrolides with promising therapeutic potential against multiple diseases, including viral infection, osteoporosis, and...
2.
Canardo G, Galvez J, Jimenez J, Serre N, Molina I, Bocanegra C
Confl Health . 2020 May; 14:21. PMID: 32377233
Background: The migration over the Mediterranean has become one of the deadliest sea voyages in last few years. The NGO Open Arms works in the area since 2015, with the...
3.
Galvez J, Galvez J, Garcia-Penarrubia P
Front Immunol . 2019 Mar; 10:349. PMID: 30886616
On the T-cell surface the TCR is the only molecule that senses antigen, and the engagement of TCR with its specific antigenic peptide (agonist)/MHC complex (pMHC) is determined by the...
4.
Ruiz-Alcaraz A, Carmona-Martinez V, Guirado A, Galvez J, Martinez-Esparza M, Garcia-Penarrubia P
Naunyn Schmiedebergs Arch Pharmacol . 2018 Nov; 392(2):219-227. PMID: 30465054
Pteridines are bicyclic heterocyclic compounds with a pyrazino[2,3-d]pyrimidine nucleus that have shown a wide range of therapeutic utilities. Concretely, 4-aminopteridine derivatives have demonstrated both anti-inflammatory and anti-cancer properties, and some...
5.
Ruiz-Alcaraz A, Tristan-Manzano M, Guirado A, Galvez J, Martinez-Esparza M, Garcia-Penarrubia P
Eur J Pharm Sci . 2017 Jan; 99:292-298. PMID: 28057547
Inflammation is part of a complex biological response directed by the immune system to fight pathogens and maintain homeostasis. Dysregulation of the inflammatory process leads to development of chronic inflammatory...
6.
Galvez J, Galvez J, Garcia-Penarrubia P
Front Immunol . 2016 Nov; 7:467. PMID: 27881981
TCR-pMHC interaction is the keystone of the adaptive immune response. This process exhibits an impressive capacity of speed, sensitivity, and discrimination that allows detecting foreign pMHCs at very low concentration...
7.
Tristan-Manzano M, Guirado A, Martinez-Esparza M, Galvez J, Garcia-Penarrubia P, Ruiz-Alcaraz A
Curr Med Chem . 2015 Aug; 22(26):3075-108. PMID: 26264925
The study of quinoxalines has increased immeasurably during the last two decades, due firstly to their relatively simple chemical synthesis, which has generated a vast variety of compounds with diverse...
8.
Garcia-Penarrubia P, Galvez J, Galvez J
J Math Biol . 2013 Jul; 69(3):553-82. PMID: 23893005
Cell signalling processes involve receptor trafficking through highly connected networks of interacting components. The binding of surface receptors to their specific ligands is a key factor for the control and...
9.
Guirado A, Lopez Sanchez J, Ruiz-Alcaraz A, Garcia-Penarrubia P, Bautista D, Galvez J
Eur J Med Chem . 2013 Jul; 66:269-75. PMID: 23811089
A direct new synthetic method on the chemistry of benzo[g]pteridines is reported. Reactions between 5,8-dichloro-2,3-dicyanoquinoxaline and benzamidines gave 4-amino-2-aryl-6,9-dichlorobenzo[g]pteridines in high to quantitative yields. The molecular structure of an N-acetyl...
10.
Guirado A, Lopez Sanchez J, Ruiz-Alcaraz A, Bautista D, Galvez J
Eur J Med Chem . 2012 May; 54:87-94. PMID: 22621841
An efficient synthetic method for previously unattainable 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines has been established. Reactions between 5,8-dichloro-2,3-dicyanoquinoxaline and alcohols in the presence of triethylamine led to 3-alkoxy-5,8-dichloro-2-cyanoquinoxalines in high to quantitative yields. These...