Jessica E Antosiewicz-Bourget
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Explore the profile of Jessica E Antosiewicz-Bourget including associated specialties, affiliations and a list of published articles.
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5
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2878
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Recent Articles
1.
Dixon J, Jung I, Selvaraj S, Shen Y, Antosiewicz-Bourget J, Lee A, et al.
Nature
. 2015 Feb;
518(7539):331-6.
PMID: 25693564
Higher-order chromatin structure is emerging as an important regulator of gene expression. Although dynamic chromatin structures have been identified in the genome, the full scope of chromatin dynamics during mammalian...
2.
Xie W, Schultz M, Lister R, Hou Z, Rajagopal N, Ray P, et al.
Cell
. 2013 May;
153(5):1134-48.
PMID: 23664764
Epigenetic mechanisms have been proposed to play crucial roles in mammalian development, but their precise functions are only partially understood. To investigate epigenetic regulation of embryonic development, we differentiated human...
3.
Hawkins R, Hon G, Yang C, Antosiewicz-Bourget J, Lee L, Ngo Q, et al.
Cell Res
. 2011 Aug;
21(10):1393-409.
PMID: 21876557
Pluripotency, the ability of a cell to differentiate and give rise to all embryonic lineages, defines a small number of mammalian cell types such as embryonic stem (ES) cells. While...
4.
Winkler T, Cantilena A, Metais J, Xu X, Nguyen A, Borate B, et al.
Stem Cells
. 2010 Feb;
28(4):687-94.
PMID: 20166152
Derivation of induced pluripotent stem (iPS) cells requires the expression of defined transcription factors (among Oct3/4, Sox2, Klf4, c-Myc, Nanog, and Lin28) in the targeted cells. Lentiviral or standard retroviral...
5.
Heintzman N, Hon G, Hawkins R, Kheradpour P, Stark A, Harp L, et al.
Nature
. 2009 Mar;
459(7243):108-12.
PMID: 19295514
The human body is composed of diverse cell types with distinct functions. Although it is known that lineage specification depends on cell-specific gene expression, which in turn is driven by...