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Jesse Saunders

Explore the profile of Jesse Saunders including associated specialties, affiliations and a list of published articles. Areas
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Citations 118
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Recent Articles
1.
Ghiuzeli C, Styblo M, Saunders J, Calabro A, Budman D, Allen S, et al.
Leuk Lymphoma . 2021 Oct; 63(3):653-663. PMID: 34689693
Arsenic trioxide (ATO) treats Acute Promyelocytic Leukemia (APL). ATO is converted from inorganic arsenic (iAs) to methylated (MAs) and dimethylated (DMAs) metabolites, which are excreted in the urine. Methylation of...
2.
Douillet C, Currier J, Saunders J, Bodnar W, Matousek T, Styblo M
Toxicol Appl Pharmacol . 2012 Dec; 267(1):11-5. PMID: 23261974
Epidemiologic evidence has linked chronic exposure to inorganic arsenic (iAs) with an increased prevalence of diabetes mellitus. Laboratory studies have identified several mechanisms by which iAs can impair glucose homeostasis....
3.
Tsang V, Fry R, Niculescu M, Rager J, Saunders J, Paul D, et al.
Toxicol Appl Pharmacol . 2012 Sep; 264(3):439-50. PMID: 22959928
Inorganic arsenic (iAs) is a complete transplacental carcinogen in mice. Previous studies have demonstrated that in utero exposure to iAs promotes cancer in adult mouse offspring, possibly acting through epigenetic...
4.
Hughes M, Edwards B, Herbin-Davis K, Saunders J, Styblo M, Thomas D
Toxicol Appl Pharmacol . 2010 Oct; 249(3):217-23. PMID: 20887743
Arsenic (+3 oxidation state) methyltransferase (As3mt) catalyzes formation of mono-, di-, and tri-methylated metabolites of inorganic arsenic. Distribution and retention of arsenic were compared in adult female As3mt knockout mice...