Jesse J Savage
Overview
Explore the profile of Jesse J Savage including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
309
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Recent Articles
11.
Pfaeffle R, Savage J, Hunter C, Palme C, Ahlmann M, Kumar P, et al.
J Clin Endocrinol Metab
. 2007 Mar;
92(5):1909-19.
PMID: 17327381
Context: The Lhx3 LIM-homeodomain transcription factor gene is required for development of the pituitary and motoneurons in mice. Human LHX3 gene mutations have been reported in five subjects with a...
12.
Savage J, Mullen R, Sloop K, Colvin S, Camper S, Franklin C, et al.
J Cell Physiol
. 2007 Feb;
212(1):105-17.
PMID: 17311285
The LHX3 transcription factor plays critical roles in pituitary and nervous system development. Mutations in the human LHX3 gene cause severe hormone deficiency diseases. The gene produces two mRNAs which...
13.
Mullen R, Colvin S, Hunter C, Savage J, Walvoord E, Bhangoo A, et al.
Mol Cell Endocrinol
. 2007 Jan;
265-266:190-5.
PMID: 17210222
The LHX3 and LHX4 LIM-homeodomain transcription factors play essential roles in pituitary gland and nervous system development. Mutations in the genes encoding these regulatory proteins are associated with combined hormone...
14.
Crowell P, Schmidt C, Yip-Schneider M, Savage J, Hertzler 2nd D, Cummings W
Neoplasia
. 2006 Jul;
8(6):437-45.
PMID: 16820089
Cyclooxygenase-2 (COX-2) has been implicated in the development of gastrointestinal malignancies. The aim of the present study was to determine COX-2 expression/activity throughout stages of experimental and human pancreatic neoplasia....
15.
Bhangoo A, Hunter C, Savage J, Anhalt H, Pavlakis S, Walvoord E, et al.
J Clin Endocrinol Metab
. 2006 Jan;
91(3):747-53.
PMID: 16394081
Context: LHX3 encodes LIM homeodomain class transcription factors with important roles in pituitary and nervous system development. The only previous report of LHX3 mutations described patients with two types of...
16.
Yaden B, Savage J, Hunter C, Rhodes S
Mol Biol Rep
. 2005 May;
32(1):1-6.
PMID: 15865204
LHX3 is a LIM homeodomain transcription factor with established roles in pituitary and nervous system development. Mutations in the human LHX3 gene are associated with severe hormone deficiency diseases. Previous...
17.
West B, Parker G, Savage J, Kiratipranon P, Toomey K, Beach L, et al.
Endocrinology
. 2004 Jul;
145(11):4866-79.
PMID: 15271874
FSH is a critical hormone regulator of gonadal function that is secreted from the pituitary gonadotrope cell. Human patients and animal models with mutations in the LHX3 LIM-homeodomain transcription factor...
18.
Savage J, Yaden B, Kiratipranon P, Rhodes S
Gene
. 2003 Nov;
319:1-19.
PMID: 14597167
The mammalian anterior pituitary gland is a compound endocrine organ that regulates reproductive development and fitness, growth, metabolic homeostasis, the response to stress, and lactation, by actions on target organs...