Jesper Velgaard Olsen
Overview
Explore the profile of Jesper Velgaard Olsen including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
23
Citations
433
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0
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Recent Articles
1.
Jorgensen S, Emdal K, Pedersen A, Axelsen L, Kildegaard H, Demozay D, et al.
Sci Rep
. 2024 Nov;
14(1):28856.
PMID: 39572596
Insulin resistance impairs the cellular insulin response, and often precedes metabolic disorders, like type 2 diabetes, impacting an increasing number of people globally. Understanding the molecular mechanisms in hepatic insulin...
2.
Batth T, Locard-Paulet M, Doncheva N, Lopez Mendez B, Jensen L, Olsen J
Nat Commun
. 2024 Oct;
15(1):8923.
PMID: 39414818
Proteins are the primary targets of almost all small molecule drugs. However, even the most selectively designed drugs can potentially target several unknown proteins. Identification of potential drug targets can...
3.
Mirian C, Ostergaard O, Thastrup M, Modvig S, Foss-Skiftesvik J, Skjoth-Rasmussen J, et al.
J Proteome Res
. 2024 Oct;
23(11):5048-5063.
PMID: 39382389
The cerebrospinal fluid (CSF) is a key matrix for discovery of biomarkers relevant for prognosis and the development of therapeutic targets in pediatric central nervous system malignancies. However, the wide...
4.
Song J, Li Z, Zhou L, Chen X, Sew W, Herranz H, et al.
Nat Commun
. 2024 Aug;
15(1):7144.
PMID: 39164296
FOXO transcription factors modulate aging-related pathways and influence longevity in multiple species, but the transcriptional targets that mediate these effects remain largely unknown. Here, we identify an evolutionarily conserved FOXO...
5.
Warner H, Franciosa G, van der Borg G, Coenen B, Faas F, Koenig C, et al.
Cell Rep
. 2024 Feb;
43(3):113866.
PMID: 38416638
To mount an adaptive immune response, dendritic cells must migrate to lymph nodes to present antigens to T cells. Critical to 3D migration is the nucleus, which is the size-limiting...
6.
Mirian C, Thastrup M, Mathiasen R, Schmiegelow K, Olsen J, Ostergaard O
Fluids Barriers CNS
. 2024 Feb;
21(1):14.
PMID: 38350915
Background: The cerebrospinal fluid (CSF) proteome could offer important insights into central nervous system (CNS) malignancies. To advance proteomic research in pediatric CNS cancer, the current study aims to (1)...
7.
Snieckute G, Ryder L, Vind A, Wu Z, Arendrup F, Stoneley M, et al.
Science
. 2023 Dec;
382(6675):eadf3208.
PMID: 38060659
The ribotoxic stress response (RSR) is a signaling pathway in which the p38- and c-Jun N-terminal kinase (JNK)-activating mitogen-activated protein kinase kinase kinase (MAP3K) ZAKα senses stalling and/or collision of...
8.
Chauhan C, Martinez-Val A, Niedenthal R, Olsen J, Kotlyarov A, Bekker-Jensen S, et al.
Cell Death Discov
. 2023 Jan;
9(1):14.
PMID: 36658119
The TNF receptor-interacting protein kinases (RIPK)-1 and 3 are regulators of extrinsic cell death response pathways, where RIPK1 makes the cell survival or death decisions by associating with distinct complexes...
9.
Kverneland A, Ostergaard O, Emdal K, Marie Svane I, Olsen J
Proteomics
. 2022 Nov;
23(7-8):e2200039.
PMID: 36398564
Human plasma is a rich source of biomedical information and biomarkers. However, the enormous dynamic range of plasma proteins limits its accessibility to mass spectrometric (MS) analysis. Here, we show...
10.
Nordgaard C, Vind A, Stonadge A, Kjobsted R, Snieckute G, Antas P, et al.
EMBO J
. 2022 Jul;
41(17):e111650.
PMID: 35899396
Mechanical inputs give rise to p38 and JNK activation, which mediate adaptive physiological responses in various tissues. In skeletal muscle, contraction-induced p38 and JNK signaling ensure adaptation to exercise, muscle...