Jerome Samir
Overview
Explore the profile of Jerome Samir including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
345
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0
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Recent Articles
1.
Safavi A, Samir J, Singh M, Bonomi M, Louie R, Micklethwaite K, et al.
Immunol Cell Biol
. 2024 Nov;
103(1):60-72.
PMID: 39500484
Anti-CD19 Chimeric Antigen Receptor (CAR)-T cell therapies have shown promise for treating B cell malignancies, but the clinical outcome is influenced by both the CAR-T product and the patient's immune...
2.
Cai C, Keoshkerian E, Wing K, Samir J, Effenberger M, Schober K, et al.
Immunol Cell Biol
. 2024 Jun;
102(7):630-641.
PMID: 38855806
CD8 T cells recognizing their cognate antigen are typically recruited as a polyclonal population consisting of multiple clonotypes with varying T-cell receptor (TCR) affinity to the target peptide-major histocompatibility complex...
3.
Louie R, Cai C, Samir J, Singh M, Deveson I, Ferguson J, et al.
Nat Commun
. 2023 Nov;
14(1):7767.
PMID: 38012187
Chimeric antigen receptor (CAR) T cell therapy is effective in treating B cell malignancies, but factors influencing the persistence of functional CAR T cells, such as product composition, patients' lymphodepletion,...
4.
Ghita L, Yao Z, Xie Y, Duran V, Cagirici H, Samir J, et al.
Nat Immunol
. 2023 Oct;
24(12):2150-2163.
PMID: 37872316
Severe dengue (SD) is a major cause of morbidity and mortality. To define dengue virus (DENV) target cells and immunological hallmarks of SD progression in children's blood, we integrated two...
5.
van de Sandt C, Nguyen T, Gherardin N, Crawford J, Samir J, Minervina A, et al.
Nat Immunol
. 2023 Sep;
24(11):1890-1907.
PMID: 37749325
CD8 T cells provide robust antiviral immunity, but how epitope-specific T cells evolve across the human lifespan is unclear. Here we defined CD8 T cell immunity directed at the prominent...
6.
Cai C, Samir J, Pirozyan M, Adikari T, Gupta M, Leung P, et al.
Nat Commun
. 2022 Dec;
13(1):7543.
PMID: 36477661
T cell exhaustion is a hallmark of hepatitis C virus (HCV) infection and limits protective immunity in chronic viral infections and cancer. Limited knowledge exists of the initial viral and...
7.
Goncharov M, Bagaev D, Shcherbinin D, Zvyagin I, Bolotin D, Thomas P, et al.
Nat Methods
. 2022 Aug;
19(9):1017-1019.
PMID: 35970936
No abstract available.
8.
Sullivan L, Nguyen T, Harpur C, Stankovic S, Kanagarajah A, Koutsakos M, et al.
Sci Immunol
. 2021 Apr;
6(58).
PMID: 33893172
Human cytomegalovirus (CMV) infection can stimulate robust human leukocyte antigen (HLA)-E-restricted CD8 T cell responses. These T cells recognize a peptide from UL40, which differs by as little as a...
9.
Zhao Y, Cai C, Samir J, Palgen J, Keoshkerian E, Li H, et al.
Eur J Immunol
. 2021 Apr;
51(7):1732-1747.
PMID: 33844287
Long-lived T-memory stem cells (T ) are key to both naturally occurring and vaccine-conferred protection against infection. These cells are characterized by the CD45RA CCR7 CD95 phenotype. Significant heterogeneity within...
10.
Samir J, Rizzetto S, Gupta M, Luciani F
BMC Med Genomics
. 2020 Feb;
13(1):29.
PMID: 32070336
Background: Single cell RNA sequencing provides unprecedented opportunity to simultaneously explore the transcriptomic and immune receptor diversity of T and B cells. However, there are limited tools available that simultaneously...