Jerome Ezan
Overview
Explore the profile of Jerome Ezan including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
646
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Recent Articles
1.
Depret N, Gleizes M, Moreau M, Poirault-Chassac S, Quiedeville A, Carvalho S, et al.
Prog Neurobiol
. 2025 Feb;
246:102728.
PMID: 39956311
In the hippocampus, dentate gyrus granule cells connect to CA3 pyramidal cells via their axons, the mossy fibers (Mf). The synaptic terminals of Mfs (Mf boutons, MfBs) form large and...
2.
Dorrego-Rivas A, Ezan J, Moreau M, Poirault-Chassac S, Aubailly N, De Neve J, et al.
Sci Adv
. 2022 Sep;
8(36):eabo6333.
PMID: 36083912
Core planar cell polarity (PCP) genes, which are involved in various neurodevelopmental disorders such as neural tube closure, epilepsy, and autism spectrum disorder, have poorly defined molecular signatures in neurons,...
3.
Ezan J, Moreau M, Mamo T, Shimbo M, Decroo M, Sans N, et al.
Front Genet
. 2022 Jun;
13:872700.
PMID: 35692812
Scribble (Scrib) is a conserved polarity protein acting as a scaffold involved in multiple cellular and developmental processes. Recent evidence from our group indicates that is also essential for brain...
4.
Moreau M, Pietropaolo S, Ezan J, Robert B, Miraux S, Maitre M, et al.
Cells
. 2022 May;
11(10).
PMID: 35626639
Social behavior is a basic domain affected by several neurodevelopmental disorders, including ASD and a heterogeneous set of neuropsychiatric disorders. The gene that codes for the polarity protein SCRIBBLE has...
5.
Ezan J, Moreau M, Mamo T, Shimbo M, Decroo M, Richter M, et al.
Sci Rep
. 2021 Apr;
11(1):9106.
PMID: 33907211
Neurodevelopmental disorders arise from combined defects in processes including cell proliferation, differentiation, migration and commissure formation. The evolutionarily conserved tumor-suppressor protein Scribble (Scrib) serves as a nexus to transduce signals...
6.
Ossipova O, Itoh K, Radu A, Ezan J, Sokol S
Development
. 2020 Aug;
147(17).
PMID: 32859582
Among the three embryonic germ layers, the mesoderm plays a central role in the establishment of the vertebrate body plan. The mesoderm is specified by secreted signaling proteins from the...
7.
Messeant J, Ezan J, Delers P, Glebov K, Marchiol C, Lager F, et al.
Development
. 2017 Mar;
144(9):1712-1724.
PMID: 28348167
Understanding the developmental steps that shape formation of the neuromuscular junction (NMJ) connecting motoneurons to skeletal muscle fibers is crucial. Wnt morphogens are key players in the formation of this...
8.
Ezan J, Montcouquiol M
Med Sci (Paris)
. 2014 Nov;
30(11):1004-10.
PMID: 25388583
Since our seminal study in 2003, much has been written about core planar cell polarity (core PCP) signaling and the inner ear. In just a few years, and using the...
9.
Piguel N, Fievre S, Blanc J, Carta M, Moreau M, Moutin E, et al.
Cell Rep
. 2014 Oct;
9(2):712-27.
PMID: 25310985
The appropriate trafficking of glutamate receptors to synapses is crucial for basic synaptic function and synaptic plasticity. It is now accepted that NMDA receptors (NMDARs) internalize and are recycled at...
10.
Ezan J, Lasvaux L, Gezer A, Novakovic A, May-Simera H, Belotti E, et al.
Nat Cell Biol
. 2013 Aug;
15(9):1107-15.
PMID: 23934215
In ciliated mammalian cells, the precise migration of the primary cilium at the apical surface of the cells, also referred to as translational polarity, defines planar cell polarity (PCP) in...