Jerome Eeckhoute
Overview
Explore the profile of Jerome Eeckhoute including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
73
Citations
14470
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Berthier A, Gheeraert C, Vinod M, Johanns M, Guille L, Haas J, et al.
J Hepatol
. 2025 Feb;
PMID: 39947330
Background: Metabolic flexibility (MetF) is an organism's ability to adjust to changing metabolic supplies and energy demands. Insulin plays a central role in coordinating MetF through molecular mechanisms such as...
2.
Very N, Staels B, Eeckhoute J
Trends Cell Biol
. 2024 Nov;
34(12):988-991.
PMID: 39516052
Increased protein O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) has emerged as a hallmark of mammalian cell activation, contributing to Warburg-like metabolic rewiring allowing the acquisition of new functionalities. Recent advances indicate that O-GlcNAcylation...
3.
Dubois V, Lefebvre P, Staels B, Eeckhoute J
Gut
. 2024 Jun;
73(9):1562-1569.
PMID: 38862216
Nuclear receptors (NRs) are ligand-dependent transcription factors required for liver development and function. As a consequence, NRs have emerged as attractive drug targets in a wide range of liver diseases....
4.
Very N, Boulet C, Gheeraert C, Berthier A, Johanns M, Bou Saleh M, et al.
Cell Death Dis
. 2024 Jun;
15(6):391.
PMID: 38830870
Tissue injury causes activation of mesenchymal lineage cells into wound-repairing myofibroblasts (MFs), whose uncontrolled activity ultimately leads to fibrosis. Although this process is triggered by deep metabolic and transcriptional reprogramming,...
5.
Vinod M, Berthier A, Marechal X, Gheeraert C, Boutry R, Delhaye S, et al.
Nat Cardiovasc Res
. 2024 Jan;
1(11):990-1005.
PMID: 38229609
Myocardial ischemia-reperfusion injury (MIRI) induces life-threatening damages to the cardiac tissue and pharmacological means to achieve cardioprotection are sorely needed. MIRI severity varies along the day-night cycle and is molecularly...
6.
Johanns M, Haas J, Raverdy V, Vandel J, Chevalier-Dubois J, Guille L, et al.
JHEP Rep
. 2023 Dec;
6(1):100948.
PMID: 38125300
Background & Aims: Liver homeostasis is ensured in part by time-of-day-dependent processes, many of them being paced by the molecular circadian clock. Liver functions are compromised in metabolic dysfunction-associated steatotic...
7.
Clavreul L, Bernard L, Cotte A, Hennuyer N, Bourouh C, Devos C, et al.
Metabolism
. 2023 Nov;
151:155720.
PMID: 37926201
Background And Aims: Peroxisome Proliferator-Activated Receptor α (PPARα) is a key regulator of hepatic lipid metabolism and therefore a promising therapeutic target against Metabolic-dysfunction Associated Steatotic Liver Diseases (MASLD). However,...
8.
Berthier A, Gheeraert C, Johanns M, Vinod M, Staels B, Eeckhoute J, et al.
J Biol Rhythms
. 2023 Oct;
39(1):20-34.
PMID: 37872767
Circadian-paced biological processes are key to physiology and required for metabolic, immunologic, and cardiovascular homeostasis. Core circadian clock components are transcription factors whose half-life is precisely regulated, thereby controlling the...
9.
Oger F, Moreno M, Derhourhi M, Thiroux B, Berberian L, Bourouh C, et al.
iScience
. 2023 Jul;
26(7):107231.
PMID: 37496675
Histone deacetylases enzymes (HDACs) are chromatin modifiers that regulate gene expression through deacetylation of lysine residues within specific histone and non-histone proteins. A cell-specific gene expression pattern defines the identity...
10.
Dubois-Chevalier J, Gheeraert C, Berthier A, Boulet C, Dubois V, Guille L, et al.
EMBO Rep
. 2023 Jul;
24(9):e57020.
PMID: 37424431
Cell identity is specified by a core transcriptional regulatory circuitry (CoRC), typically limited to a small set of interconnected cell-specific transcription factors (TFs). By mining global hepatic TF regulons, we...