Jeroen Spanoghe
Overview
Explore the profile of Jeroen Spanoghe including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
13
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Recent Articles
1.
Spanoghe J, Wynendaele E, Vergaelen M, De Colvenaer M, Mariman T, Vonck K, et al.
J Control Release
. 2025 Mar;
:113626.
PMID: 40086757
Up to 30 % of epilepsy patients suffer from drug-resistant epilepsy (DRE). The search for innovative therapies is therefore important to close the existing treatment gap in these patients. The...
2.
Vergaelen M, Manzella S, Vonck K, Craey E, Spanoghe J, Sprengers M, et al.
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203829
The intrahippocampal kainic acid (IHKA) mouse model is an extensively used in vivo model to investigate the pathophysiology of mesial temporal lobe epilepsy (mTLE) and to develop novel therapies for...
3.
Craey E, Hulpia F, Spanoghe J, Manzella S, Larsen L, Sprengers M, et al.
Int J Mol Sci
. 2022 Aug;
23(16).
PMID: 36012151
We report the design, synthesis, and validation of the novel compound photocaged N-cyclopentyladenosine (cCPA) to achieve precisely localized and timed release of the parent adenosine A1 receptor agonist CPA using...
4.
Spanoghe J, Larsen L, Craey E, Manzella S, Van Dycke A, Boon P, et al.
Int J Mol Sci
. 2021 Jan;
22(1).
PMID: 33396826
Adenosine acts as an endogenous anticonvulsant and seizure terminator in the brain. Many of its anticonvulsive effects are mediated through the activation of the adenosine A receptor, a G protein-coupled...