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Jermaine L Ford

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Articles 11
Citations 73
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Recent Articles
1.
Murr A, Murr A, Buckalew A, Buckalew A, Devane G, Devane G, et al.
Toxicol Sci . 2024 Nov; 203(2):206-215. PMID: 39495161
We recently identified the herbicide oxyfluorfen as an inhibitor of iodide uptake by the sodium iodide symporter, a key step in thyroid hormone synthesis, using in vitro assays. We also...
2.
OShaughnessy K, Bell K, Sasser A, Gilbert M, Riutta C, Ford J, et al.
Environ Int . 2024 Jul; 190:108838. PMID: 38963985
Known as "forever chemicals", per- and polyfluoroalkyl substances (PFAS) are synthetic compounds used in consumer goods but pose significant public health concerns, including disruption of the thyroid system. As thyroid...
3.
Moore M, Ford J, Schladweiler M, Dye J, Jackson T, Miller C
Metabolomics . 2024 Mar; 20(2):40. PMID: 38460019
Introduction: Studies of gastrointestinal physiology and the gut microbiome often consider the influence of intestinal region on experimental endpoints. However, this same consideration is not often applied to the gut...
4.
Gilbert M, Hassan I, OShaughnessy K, Wood C, Stoker T, Riutta C, et al.
Toxicol Sci . 2023 Dec; 198(1):113-127. PMID: 38145495
The environmental contaminant perchlorate impairs the synthesis of thyroid hormones by reducing iodine uptake into the thyroid gland. Despite this known action, moderate doses of perchlorate do not significantly alter...
5.
Gilbert M, OShaughnessy K, Bell K, Ford J
Toxics . 2023 Dec; 11(12). PMID: 38133428
Environmental contaminants are often flagged as thyroid system disruptors due to their actions to reduce serum thyroxine (T4) in rodent models. The presence of a periventricular heterotopia (PVH), a brain...
6.
Renyer A, Ravindra K, Wetmore B, Ford J, Devito M, Hughes M, et al.
Toxics . 2023 Dec; 11(12). PMID: 38133352
Few studies are available on the environmental and toxicological effects of perfluoroalkyl ether carboxylic acids (PFECAs), such as GenX, which are replacing legacy PFAS in manufacturing processes. To collect initial...
7.
OShaughnessy K, Sasser A, Bell K, Riutta C, Ford J, Grindstaff R, et al.
Toxicol Sci . 2023 Dec; 198(1):128-140. PMID: 38070162
Evaluating the neurodevelopmental effects of thyroid-disrupting chemicals is challenging. Although some standardized developmental and reproductive toxicity studies recommend serum thyroxine (T4) measures in developing rats, extrapolating between a serum T4...
8.
OShaughnessy K, McMichael B, Sasser A, Bell K, Riutta C, Ford J, et al.
Front Endocrinol (Lausanne) . 2023 Feb; 14:1090081. PMID: 36843608
Thyroid hormone (TH) action controls brain development in a spatiotemporal manner. Previously, we demonstrated that perinatal hypothyroidism led to formation of a periventricular heterotopia in developing rats. This heterotopia occurs...
9.
Gilbert M, OShaughnessy K, Thomas S, Riutta C, Wood C, Smith A, et al.
Toxicol Sci . 2022 Mar; 187(1):186. PMID: 35257183
No abstract available.
10.
Gilbert M, OShaughnessy K, Thomas S, Riutta C, Wood C, Smith A, et al.
Toxicol Sci . 2021 Aug; 183(1):195-213. PMID: 34460931
Many xenobiotics are identified as potential thyroid disruptors due to their action to reduce circulating levels of thyroid hormone, most notably thyroxine (T4). Developmental neurotoxicity is a primary concern for...