Jeremy Chase Crawford
Overview
Explore the profile of Jeremy Chase Crawford including associated specialties, affiliations and a list of published articles.
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75
Citations
3230
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Recent Articles
1.
Perry S, Brice D, Sakr A, Kandeil A, DeBeauchamp J, Ghonim M, et al.
J Virol
. 2025 Jan;
99(2):e0146024.
PMID: 39791909
Importance: To develop effective interventions against influenza, it is important to identify host factors affecting pathogenesis and immune responses. Tonsils are lymphoepithelial organs characterized by infiltration of B and T...
2.
Borcherding N, Kim W, Quinn M, Han F, Zhou J, Sturtz A, et al.
Nat Immunol
. 2024 Aug;
25(9):1731-1741.
PMID: 39164479
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and mRNA vaccination induce robust CD4 T cell responses. Using single-cell transcriptomics, here, we evaluated CD4 T cells specific for the SARS-CoV-2...
3.
Schattgen S, Turner J, Ghonim M, Crawford J, Schmitz A, Kim H, et al.
Nat Immunol
. 2024 Aug;
25(9):1742-1753.
PMID: 39164477
The differentiation and specificity of human CD4 T follicular helper cells (T cells) after influenza vaccination have been poorly defined. Here we profiled blood and draining lymph node (LN) samples...
4.
Jia X, Crawford J, Gebregzabher D, Monson E, Mettelman R, Wan Y, et al.
Cell
. 2024 Aug;
187(17):4586-4604.e20.
PMID: 39137778
Respiratory infections cause significant morbidity and mortality, yet it is unclear why some individuals succumb to severe disease. In patients hospitalized with avian A(H7N9) influenza, we investigated early drivers underpinning...
5.
Rodriguez D, Tummers B, Shaw J, Quarato G, Weinlich R, Cripps J, et al.
Cell Rep
. 2024 Jun;
43(6):114335.
PMID: 38850531
Perturbation of the apoptosis and necroptosis pathways critically influences embryogenesis. Receptor-associated protein kinase-1 (RIPK1) interacts with Fas-associated via death domain (FADD)-caspase-8-cellular Flice-like inhibitory protein long (cFLIP) to regulate both extrinsic...
6.
Gautam A, Boyd D, Nikhar S, Zhang T, Siokas I, Van de Velde L, et al.
Nature
. 2024 Apr;
628(8009):835-843.
PMID: 38600381
Severe influenza A virus (IAV) infections can result in hyper-inflammation, lung injury and acute respiratory distress syndrome (ARDS), for which there are no effective pharmacological therapies. Necroptosis is an attractive...
7.
Kirk A, Crawford J, Chou C, Guy C, Pandey K, Kozlik T, et al.
Cell Rep Med
. 2024 Mar;
5(3):101469.
PMID: 38508137
Fibrolamellar carcinoma (FLC) is a liver tumor with a high mortality burden and few treatment options. A promising therapeutic vulnerability in FLC is its driver mutation, a conserved DNAJB1-PRKACA gene...
8.
Haydar D, Ibanez-Vega J, Crawford J, Chou C, Guy C, Meehl M, et al.
Cancer Res Commun
. 2023 Nov;
3(12):2430-2446.
PMID: 37971169
Significance: CAR T-cell immunotherapies hold great potential for treating brain cancers; however, they are hindered by a challenging immune environment that dampens their effectiveness. In this study, we show that...
9.
Lareau C, Yin Y, Maurer K, Sandor K, Daniel B, Yagnik G, et al.
Nature
. 2023 Nov;
623(7987):608-615.
PMID: 37938768
Cell therapies have yielded durable clinical benefits for patients with cancer, but the risks associated with the development of therapies from manipulated human cells are understudied. For example, we lack...
10.
van de Sandt C, Nguyen T, Gherardin N, Crawford J, Samir J, Minervina A, et al.
Nat Immunol
. 2023 Sep;
24(11):1890-1907.
PMID: 37749325
CD8 T cells provide robust antiviral immunity, but how epitope-specific T cells evolve across the human lifespan is unclear. Here we defined CD8 T cell immunity directed at the prominent...