Jeremiah J Trausch
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Explore the profile of Jeremiah J Trausch including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
382
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Recent Articles
1.
Roman J, Ge S, Bouaraphan S, Fink M, Trausch J, Verch T
Anal Chem
. 2024 Feb;
96(8):3489-3497.
PMID: 38349730
Selection and characterization of antibodies are critically important in establishing robust immunoassays to support the development efforts of vaccines. Plate-based ELISA can be time- and resource-intensive to select initial antibody...
2.
Chozinski T, Ferguson B, Fisher W, Ge S, Gong Q, Kang H, et al.
Anal Chem
. 2022 Apr;
94(16):6146-6155.
PMID: 35410467
Global deployment of vaccines poses significant challenges in the distribution and use of the accompanying immunoassays, one of the standard methods for quality control of vaccines, particularly when establishing assays...
3.
Verch T, Trausch J, Shank-Retzlaff M
Bioanalysis
. 2018 Jan;
10(3):163-180.
PMID: 29333863
Compared with biologics, vaccine potency assays represent a special challenge due to their unique compositions, multivalency, long life cycles and global distribution. Historically, vaccines were released using in vivo potency...
4.
Trausch J, Shank-Retzlaff M, Verch T
Vaccine
. 2017 Apr;
35(41):5495-5502.
PMID: 28433327
Vaccine in vitro potency assays are vital regulatory tests that are used to confirm the presence and concentration of an antigen of interest in a form that directly or indirectly...
5.
Trausch J, Shank-Retzlaff M, Verch T
Anal Chem
. 2017 Feb;
89(6):3554-3561.
PMID: 28233502
Measuring vaccine potency is critical for vaccine release and is often accomplished using antibody-based ELISAs. Antibodies can be associated with significant drawbacks that are often overlooked including lot-to-lot variability, problems...
6.
Miao Z, Adamiak R, Antczak M, Batey R, Becka A, Biesiada M, et al.
RNA
. 2017 Feb;
23(5):655-672.
PMID: 28138060
RNA-Puzzles is a collective experiment in blind 3D RNA structure prediction. We report here a third round of RNA-Puzzles. Five puzzles, 4, 8, 12, 13, 14, all structures of riboswitch...
7.
Trausch J, Marcano-Velazquez J, Matyjasik M, Batey R
Chem Biol
. 2015 Jul;
22(7):829-37.
PMID: 26144884
The ZTP riboswitch is a widespread family of regulatory RNAs that upregulate de novo purine synthesis in response to increased intracellular levels of ZTP or ZMP. As an important intermediate...
8.
Trausch J, Batey R
Methods Enzymol
. 2015 Jan;
550:41-71.
PMID: 25605380
Genetically encodable RNA devices that directly detect small molecules in the cellular environment are of increasing interest for a variety of applications including live cell imaging and synthetic biology. Riboswitches...
9.
Trausch J, Xu Z, Edwards A, Reyes F, Ross P, Knight R, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(18):6624-9.
PMID: 24753586
In bacteria, sulfur metabolism is regulated in part by seven known families of riboswitches that bind S-adenosyl-l-methionine (SAM). Direct binding of SAM to these mRNA regulatory elements governs a downstream...
10.
Trausch J, Batey R
Chem Biol
. 2014 Jan;
21(2):205-16.
PMID: 24388757
The tetrahydrofolate (THF) riboswitch regulates folate transport and metabolism in a number of Firmicutes by cooperatively binding two molecules of THF. To further understand this riboswitch's specificity for THF, binding...