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Jeong-In Baek

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Articles 39
Citations 522
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Recent Articles
1.
Kim Y, Baek J, Lee K, Kim U
Free Radic Biol Med . 2023 Apr; 204:177-183. PMID: 37119862
Aminoglycoside, a medicinal category of antibiotics, are used in treatment of Gram-negative bacterial infections. Although they are the most widely-used antibiotics due to their high efficacy and low cost, several...
2.
Baek J, Kim Y, Lee K, Kim U
Front Pharmacol . 2023 Apr; 14:1176881. PMID: 37063286
Noise (noise-induced hearing loss), and ototoxic drugs (drug-induced ototoxicity), and aging (age-related hearing loss) are the major environmental factors that lead to acquired sensorineural hearing loss. So far, there have...
3.
Kim Y, Kim H, Lee B, Baek J, Lee K, Park H, et al.
Genes Genomics . 2023 Jan; 45(2):225-230. PMID: 36630074
Backgound: Hereditary hearing loss is one of the most common genetically heterogeneous defects in human. About 70% of hereditary hearing loss is defined as non-syndromic hearing loss showing loss of...
4.
Kim J, Baek J, Lee I, Kim U, Kim Y, Lee K
Genes Genomics . 2021 Nov; 44(1):1-7. PMID: 34800260
Background: Cisplatin (CP) is an effective anticancer drug broadly used for various types of cancers, but it has shown ototoxicity that results from oxidative stress. Berberine has been reported for...
5.
Kim Y, Kwon T, Kim U, Lee I, Lee K, Baek J
Antioxidants (Basel) . 2021 Oct; 10(10). PMID: 34679662
Drug-induced hearing loss is a major type of acquired sensorineural hearing loss. Cisplatin and aminoglycoside antibiotics have been known to cause ototoxicity, and excessive accumulation of intracellular reactive oxygen species...
6.
Lee H, Kim Y, Lee I, Kim U, Baek J, Lee K
Biomed Pharmacother . 2020 Mar; 126:110068. PMID: 32203888
Cisplatin (CP) is a chemotherapeutic drug used to treat cancerous solid tumors, but it causes serious side effects, including ototoxicity. The major cause of CP-induced ototoxicity is increased levels of...
7.
Lee B, Kim Y, Kim S, Goh S, Kim J, Oh S, et al.
Hum Mutat . 2019 Apr; 40(8):1172-1180. PMID: 31033086
One of most important factors for messenger RNA (mRNA) transcription is the spliceosomal component U1 small nuclear RNA (snRNA), which recognizes 5' splicing donor sites at specific regions in pre-mRNA....
8.
Lee B, Baek J, Min H, Bae S, Moon K, Kim M, et al.
Mol Neurobiol . 2019 Jan; 56(3):2300. PMID: 30637586
The original article contains an error for a grant number in the Acknowledgements section.
9.
Kim Y, Baek J, Kim S, Kim M, Lee B, Ryu N, et al.
Redox Biol . 2018 Dec; 20:544-555. PMID: 30508699
Mitochondrial NADP-dependent isocitrate dehydrogenase 2 (IDH2) is a major NADPH-producing enzyme which is essential for maintaining the mitochondrial redox balance in cells. We sought to determine whether IDH2 deficiency induces...
10.
Kim K, Lee B, Kim Y, Kim M, Ryu N, Jung D, et al.
Cell Death Dis . 2018 Aug; 9(8):827. PMID: 30068942
Cisplatin, a small platinum-containing molecule, is a widely used, highly effective anticancer drug. However, severe side effects have been found in cancer patients treated with cisplatin, including nephrotoxicity, neurotoxicity, and...