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Jens Mollerup

Explore the profile of Jens Mollerup including associated specialties, affiliations and a list of published articles. Areas
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Citations 245
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Recent Articles
11.
Garcia-Caballero T, Grabau D, Green A, Gregory J, Schad A, Kohlwes E, et al.
Histopathology . 2010 May; 56(4):472-80. PMID: 20459554
Aims: Fluorescence in situ hybridization (FISH) can be used to reveal several genomic imbalances relevant to proper cancer diagnosis and to the correct treatment regime. However, FISH requires expensive and...
12.
la Cour J, Hoj B, Mollerup J, Simon R, Sauter G, Berchtold M
Mol Oncol . 2009 Apr; 1(4):431-9. PMID: 19383317
The apoptosis linked gene-2 (ALG-2), discovered as a proapoptotic calcium binding protein, has recently been found upregulated in lung cancer tissue indicating that this protein may play a role in...
13.
Hoj B, la Cour J, Mollerup J, Berchtold M
Biochem Biophys Res Commun . 2008 Nov; 378(1):145-8. PMID: 19013425
ALG-2 (apoptosis-linked gene-2 encoded protein) has been shown to be upregulated in a variety of human tumors questioning its previously assumed pro-apoptotic function. The aim of the present study was...
14.
Draeby I, Woods Y, la Cour J, Mollerup J, Bourdon J, Berchtold M
Arch Biochem Biophys . 2007 Sep; 467(1):87-94. PMID: 17889823
ALG-2 (apoptosis linked gene 2 product) is a calcium binding protein for which no clear cellular function has been established. In this study we identified Scotin as a novel ALG-2...
15.
Mollerup J, Eriksen H, Albertsen J, Wulff T, Lambert I, Hoffmann E
Cell Physiol Biochem . 2007 Jun; 20(1-4):143-56. PMID: 17595524
Murine leukotriene B(4) (LTB(4)) receptor (mBLT1) cDNA was identified by searching the EST database using human LTB(4) receptor as the query sequence. Expression of functional mBLT1 after injection of in...
16.
la Cour J, Mollerup J, Werner Berchtold M
Biochem Biophys Res Commun . 2007 Jan; 353(4):1063-7. PMID: 17214967
A variety of stimuli can trigger intracellular calcium oscillations. Relatively little is known about the molecular mechanisms decoding these events. We show that ALG-2, a Ca2+-binding protein originally isolated as...
17.
Mollerup J, Berchtold M
FEBS Lett . 2005 Jul; 579(19):4187-92. PMID: 16038904
The heat shock protein 90 co-chaperone p23 has recently been shown to be up-regulated in cancer cells and down-regulated in atheroschlerotic plaques. We found that p23 is degraded during apoptosis...
18.
Tarabykina S, Mollerup J, Winding P, Berchtold M
Front Biosci . 2004 Feb; 9:1817-32. PMID: 14977589
ALG-2 was originally discovered as a pro-apoptotic protein in a genetic screen. Due to its ability to bind calcium with high affinity it was postulated to provide a link between...
19.
Mollerup J, Krogh T, Nielsen P, Berchtold M
FEBS Lett . 2003 Dec; 555(3):478-82. PMID: 14675759
A commercial antibody (clone 22) directed against the apoptosis-linked gene 2 (alg2, pdcd6) encoded protein has been used by several groups. Up-regulated expression of the antigen was observed in primary...
20.
la Cour J, Mollerup J, Winding P, Tarabykina S, Sehested M, Berchtold M
Am J Pathol . 2003 Jun; 163(1):81-9. PMID: 12819013
ALG-2 was isolated in a screen for proteins involved in programmed cell death and is the first Ca(2+)-binding protein found to be directly involved in apoptosis. We have generated polyclonal...