Jennifer R Pace
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Explore the profile of Jennifer R Pace including associated specialties, affiliations and a list of published articles.
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5
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47
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Recent Articles
1.
Kim E, Onyango E, Pace J, Abbot T, Fu L, Gribble G
Tetrahedron Lett
. 2024 Aug;
57(8):864-867.
PMID: 39105101
Lactols , obtained by DIBAL reduction of their corresponding lactones , in equilibrium with their hydroxyaldehyde tautomers were used in a three-component reductive alkylation with 2-hydroxy-1,4-naphthoquinone to give a series...
2.
Pace J, Lampkin B, Abakah C, Moyer A, Miao J, Deprey K, et al.
J Am Chem Soc
. 2021 Sep;
143(37):15039-15044.
PMID: 34516087
Peptides constrained by intramolecular cross-links, especially stapled α-helices, have emerged as versatile scaffolds for drug development. However, there are fewer examples of similarly constrained scaffolds for other secondary structures. Here,...
3.
Pace J, Jog R, Burgess D, Hadden M
J Liposome Res
. 2019 Oct;
30(3):305-311.
PMID: 31576768
Itraconazole (ITZ) is an FDA-approved antifungal agent that has recently been explored for novel biological properties. In particular, ITZ was identified as a potent inhibitor of the hedgehog (Hh) pathway,...
4.
Pace J, Teske K, Chau L, Dash R, Zaino A, Wechsler-Reya R, et al.
J Med Chem
. 2019 Mar;
62(8):3873-3885.
PMID: 30896941
The Food and Drug Administration-approved antifungal agent, itraconazole (ITZ), has been increasingly studied for its novel biological properties. In particular, ITZ inhibits the hedgehog (Hh) signaling pathway and has the...
5.
Pace J, DeBerardinis A, Sail V, Tacheva-Grigorova S, Chan K, Tran R, et al.
J Med Chem
. 2016 Mar;
59(8):3635-49.
PMID: 27014922
Itraconazole (ITZ) is an FDA-approved member of the triazole class of antifungal agents. Two recent drug repurposing screens identified ITZ as a promising anticancer chemotherapeutic that inhibits both the angiogenesis...