Jennifer R Lynch
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Explore the profile of Jennifer R Lynch including associated specialties, affiliations and a list of published articles.
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7
Citations
80
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Recent Articles
1.
Lynch J, Navarro M, Kennedy A, Robertson S, Mulvey R, Hernan-Gomez A
Chemistry
. 2024 Dec;
31(5):e202403544.
PMID: 39625168
Literature on Group One organoelement chemistry is dominated by lithium, though sodium and potassium also feature prominently, whereas rubidium and caesium are rarely mentioned. With recent breakthroughs hinting that organoelement...
2.
Lynch J, Kennedy A, Barker J, Mulvey R
Chemistry
. 2023 Nov;
30(15):e202303373.
PMID: 38032346
A widely utilised class of ligands in synthesis and catalysis, β-diketiminate (BDI) or NacNac compounds were initially considered innocent in the sense that they remained intact in all their applications....
3.
Wacker J, Lynch J, Banerjee S, Macdonald P, Kennedy A, Sarkar B, et al.
Chem Commun (Camb)
. 2023 Nov;
60(1):91-94.
PMID: 38019118
Light alkali metal (Li, Na, K) amides have a long history of synthetic utility, but heavier (Rb, Cs) congeners have barely been studied. This study reveals remarkable structurally complex outcomes...
4.
Gauld R, Lynch J, Kennedy A, Barker J, Reid J, Mulvey R
Inorg Chem
. 2021 Apr;
60(8):6057-6064.
PMID: 33830739
Homoleptic LiNacNac forms simple donor-acceptor complexes with ,'-dicyclohexylcarbodiimide (CyN═C═NCy), triphenylphosphine oxide (PhP═O), and benzophenone (PhCO). These crystallographically characterized compounds could be regarded as model intermediates en route to reducing the...
5.
Lynch J, Salik B, Connerty P, Vick B, Leung H, Pijning A, et al.
Leukemia
. 2019 Jan;
33(6):1400-1410.
PMID: 30622285
Abnormal metabolism is a fundamental hallmark of cancer and represents a therapeutic opportunity, yet its regulation by oncogenes remains poorly understood. Here, we uncover that JMJD1C, a jumonji C (JmjC)-containing...
6.
Lynch J, Wang J
Int J Mol Sci
. 2016 May;
17(5).
PMID: 27187360
G protein-coupled receptors (GPCRs) are a large superfamily of cell-surface signaling proteins that bind extracellular ligands and transduce signals into cells via heterotrimeric G proteins. GPCRs are highly tractable drug...
7.
Dietrich P, Yang C, Leung H, Lynch J, Gonzales E, Liu B, et al.
Blood
. 2014 Oct;
124(22):3284-94.
PMID: 25293777
β-catenin is required for establishment of leukemic stem cells (LSCs) in acute myeloid leukemia (AML). Targeted inhibition of β-catenin signaling has been hampered by the lack of pathway components amenable...