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Jennifer N Rees

Explore the profile of Jennifer N Rees including associated specialties, affiliations and a list of published articles. Areas
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Citations 298
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Recent Articles
1.
Bartos J, Voicu S, Matsuura T, Tsangaris A, Sideris G, Oestreich B, et al.
JACC Basic Transl Sci . 2017 Nov; 2(3):244-253. PMID: 29152600
xtracorporeal membrane oxygenation (ECMO) is used in cardiopulmonary resuscitation (CPR) of refractory cardiac arrest. We used a 2×2 study design to compare ECMO versus CPR and epinephrine versus placebo in...
2.
Matsuura T, Bartos J, Tsangaris A, Chandra Shekar K, Olson M, Riess M, et al.
Resuscitation . 2017 Apr; 116:8-15. PMID: 28408349
Background: Out-of-hospital cardiac arrest (CA) is a prevalent medical crisis resulting in severe injury to the heart and brain and an overall survival of less than 10%. Mitochondrial dysfunction is...
3.
Bartos J, Matsuura T, Tsangaris A, Olson M, McKnite S, Rees J, et al.
JACC Basic Transl Sci . 2016 Oct; 1(4):224-234. PMID: 27695713
Background: Poloxamer 188 (P188) is a nonionic triblock copolymer believed to prevent cellular injury after ischemia and reperfusion. Objectives: This study compared intracoronary infusion of P188 immediately after reperfusion with...
4.
Debaty G, Lurie K, Metzger A, Lick M, Bartos J, Rees J, et al.
Resuscitation . 2016 May; 105:29-35. PMID: 27211835
Objective: Ischemic postconditioning (PC) using three intentional pauses at the start of cardiopulmonary resuscitation (CPR) improves outcomes after cardiac arrest in pigs when epinephrine (epi) is used before defibrillation. We...
5.
Debaty G, Matsuura T, Bartos J, Rees J, McKnite S, Lick M, et al.
Crit Care Med . 2014 Dec; 43(4):849-55. PMID: 25525755
Objectives: The aim of this study was to assess the effect of sodium nitroprusside-enhanced cardiopulmonary resuscitation on heat exchange during surface cooling. We hypothesized that sodium nitroprusside-enhanced cardiopulmonary resuscitation would...
6.
Bartos J, Matsuura T, Sarraf M, Youngquist S, McKnite S, Rees J, et al.
Resuscitation . 2014 Dec; 87:7-13. PMID: 25447036
Objective: Ischemic postconditioning (stutter CPR) and sevoflurane have been shown to mitigate the effects of reperfusion injury in cardiac tissue after 15min of ventricular fibrillation (VF) cardiac arrest. Poloxamer 188...
7.
Riess M, Matsuura T, Bartos J, Bienengraeber M, Aldakkak M, McKnite S, et al.
Resuscitation . 2014 Oct; 85(12):1745-51. PMID: 25281906
Background: Anaesthetic postconditioning (APoC) attenuates myocardial injury following coronary ischaemia/reperfusion. We hypothesised that APoC at the initiation of cardiopulmonary resuscitation (CPR) will improve post resuscitation myocardial function along with improved...
8.
Jinsmaa Y, Florang V, Rees J, Mexas L, Eckert L, Allen E, et al.
Chem Biol Interact . 2011 Jan; 192(1-2):118-21. PMID: 21238438
Dopamine (DA) undergoes monoamine oxidase catalyzed oxidative deamination to 3,4-dihydroxyphenylacetaldehyde (DOPAL), which is metabolized primarily to 3,4-dihydroxyphenylacetic acid (DOPAC) via aldehyde dehydrogenase (ALDH). Previous studies demonstrated DOPAL to be neurotoxic,...
9.
Rees J, Florang V, Eckert L, Doorn J
Chem Res Toxicol . 2009 Jun; 22(7):1256-63. PMID: 19537779
Dopamine (DA) has been implicated as an endogenous neurotoxin to explain selective neurodegeneration, as observed for Parkinson's disease (PD). However, previous work demonstrated that 3,4-dihydroxyphenylacetaldehyde (DOPAL) was more toxic than...
10.
Jinsmaa Y, Florang V, Rees J, Anderson D, Strack S, Doorn J
Chem Res Toxicol . 2009 Apr; 22(5):835-41. PMID: 19388687
Dopamine (DA) has been implicated as an endogenous neurotoxin to explain the selective neurodegeneration as observed for Parkinson's disease (PD). In addition, oxidative stress and lipid peroxidation are hypothesized culprits...