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» Authors » Jennifer L Mandzia

Jennifer L Mandzia

Explore the profile of Jennifer L Mandzia including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 22
Citations 2565
Followers 0
Related Specialties
Neurology
Cardiology & Vascular Diseases
General Medicine
Top 10 Co-Authors
Dar Dowlatshahi
Richard H Swartz
Luciano A Sposato
Michael D Hill
Demetrios J Sahlas
Bijoy K Menon
Mayank Goyal
Sandra E Black
Alexandre Y Poppe
Sebastian Fridman
Published In
Stroke
Lancet
Hum Brain Mapp
Can J Neurol Sci
Can J Cardiol
Affiliations
Soon will be listed here.
Recent Articles
1.
Efficacy and safety of nerinetide in acute ischaemic stroke in patients undergoing endovascular thrombectomy without previous thrombolysis (ESCAPE-NEXT): a multicentre, double-blind, randomised controlled trial
Hill M, Goyal M, Demchuk A, Menon B, Field T, Guest W, et al.
Lancet . 2025 Feb; 405(10478):560-570. PMID: 39955119
Background: In the ESCAPE-NA1 trial, treatment with nerinetide, an eicosapeptide that interferes with post-synaptic density protein 95, was associated with improved functional outcome among patients with acute ischaemic stroke due...
2.
Time-varying differences in stroke recurrence risk between types of atrial fibrillation based on screening methods and timing of detection
Alvarado-Bolanos A, Ayan D, Lodol F, Khaw A, Mai L, Mandzia J, et al.
Eur Stroke J . 2024 Nov; :23969873241300888. PMID: 39589013
Introduction: Atrial fibrillation (AF) burden progresses with time. Among ischemic stroke (IS) patients, AF can be detected at different burden progression stages based on the timing and screening method. We...
3.
Extended Computed Tomography Angiography for the Successful Diagnosis of Cardioaortic Thrombus in Acute Ischemic Stroke and TIA: Study Protocol for a Randomized Controlled Trial
Sposato L, Ayan D, Ahmed M, Fridman S, Mandzia J, Lodol F, et al.
Cerebrovasc Dis . 2024 Jun; :1-10. PMID: 38934129
Introduction: Cardiac imaging is one of the main components of the etiological investigation of ischemic strokes. However, basic and advanced cardiac imaging remain underused in most stroke centers globally. Computed...
4.
Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial
Coutts S, Ankolekar S, Appireddy R, Arenillas J, Assis Z, Bailey P, et al.
Lancet . 2024 May; 403(10444):2597-2605. PMID: 38768626
Background: Individuals with minor ischaemic stroke and intracranial occlusion are at increased risk of poor outcomes. Intravenous thrombolysis with tenecteplase might improve outcomes in this population. We aimed to test...
5.
Differences in Stroke Recurrence Risk Between Atrial Fibrillation Detected on ECG and 14-Day Cardiac Monitoring
Alvarado-Bolanos A, Ayan D, Khaw A, Mai L, Mandzia J, Bogiatzi C, et al.
Stroke . 2023 Jun; 54(8):2022-2030. PMID: 37377007
Background: Ischemic stroke and transient ischemic attack (TIA) standard-of-care etiological investigations include an ECG and prolonged cardiac monitoring (PCM). Atrial fibrillation (AF) detected after stroke has been generally considered a...
6.
Men Are at Higher Risk of Screening Positive for Vascular Cognitive Impairment Compared to Women after Stroke and Transient Ischemic Attack
Zinman J, Kapoor A, Si K, Sujanthan S, Southwell A, Cayley M, et al.
J Alzheimers Dis . 2023 May; 94(1):89-94. PMID: 37212109
While women have greater incidence of dementia, men have higher prevalence of vascular risk factors. This study examined sex differences in risk of screening positive for cognitive impairment after stroke....
7.
Cognitive correlates of antisaccade behaviour across multiple neurodegenerative diseases
Riek H, Brien D, Coe B, Huang J, Perkins J, Yep R, et al.
Brain Commun . 2023 Mar; 5(2):fcad049. PMID: 36970045
Oculomotor tasks generate a potential wealth of behavioural biomarkers for neurodegenerative diseases. Overlap between oculomotor and disease-impaired circuitry reveals the location and severity of disease processes via saccade parameters measured...
8.
Feasibility of deconvolution-based multiphase CT angiography perfusion maps in acute ischemic stroke: Simulation and concordance with CT perfusion
Chung K, Khaw A, Pandey S, Lee D, Mandzia J, Lee T
J Stroke Cerebrovasc Dis . 2022 Nov; 31(12):106844. PMID: 36323170
Objectives: Integration of CT perfusion (CTP) with requisite non-contrast CT and CT angiography (CTA) stroke imaging may allow efficient stroke lesion volume measurement. Using surrogate images from CTP, we simulated...
9.
Health-Related Quality of Life Among Patients With Acute Ischemic Stroke and Large Vessel Occlusion in the ESCAPE Trial
Joundi R, Rebchuk A, Field T, Smith E, Goyal M, Demchuk A, et al.
Stroke . 2021 Mar; 52(5):1636-1642. PMID: 33691504
Background And Purpose: Endovascular thrombectomy (EVT) reduces 90-day disability in patients following acute ischemic stroke due to large vessel occlusion. Patient-reported outcome measures after EVT, such as health-related quality of...
10.
Primary CNS vasculitis: A systematic review on clinical characteristics associated with abnormal biopsy and angiography
Krawczyk M, Barra L, Sposato L, Mandzia J
Autoimmun Rev . 2020 Nov; 20(1):102714. PMID: 33197577
Background: Primary Central Nervous System Vasculitis (PCNSV) remains a diagnostic challenge due to its variable and non-specific clinical manifestations. In part, the clinical heterogeneity of PCNSV may be a consequence...