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Jennifer L Chain

Explore the profile of Jennifer L Chain including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 192
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Recent Articles
1.
Chain J, Alvarez K, Mascaro-Blanco A, Reim S, Bentley R, Hommer R, et al.
Front Psychiatry . 2020 Jul; 11:564. PMID: 32670106
Movement, behavioral, and neuropsychiatric disorders in children have been linked to infections and a group of anti-neuronal autoantibodies, implying dopamine receptor-mediated encephalitis within the basal ganglia. The purpose of this...
2.
Born W, Roark C, Jin N, Wands J, Aydintug M, Huang Y, et al.
Open Immunol J . 2015 Nov; 2:143-150. PMID: 26550059
The resident population of γδ T cells in the normal lung is small but during lung inflammation, γδ T cells can increase dramatically. Histological analysis reveals diverse interactions between γδ...
3.
Neff C, Chain J, MaWhinney S, Martin A, Linderman D, Flores S, et al.
Am J Respir Crit Care Med . 2014 Dec; 191(4):464-73. PMID: 25536276
Rationale: Lymphocytic alveolitis in HIV-1-infected individuals is associated with multiple pulmonary complications and a poor prognosis. Although lymphocytic alveolitis has been associated with viremia and an increased number of CD8(+)...
4.
Chain J, Martin A, Mack D, Maier L, Palmer B, Fontenot A
J Immunol . 2013 Jul; 191(4):1648-56. PMID: 23851684
Chronic beryllium disease (CBD) is an occupational lung disorder characterized by granulomatous inflammation and the accumulation of beryllium-responsive CD4(+) T cells in the lung. These differentiated effector memory T cells...
5.
OBrien R, Chain J, Aydintug M, Bohrer-Kunter D, Huang Y, Hardy I, et al.
Invest Ophthalmol Vis Sci . 2011 Dec; 53(1):301-8. PMID: 22199243
Purpose: To investigate additional factors in the spontaneous development of keratitis previously reported in B10.TCRδ⁻/⁻ female mice. Methods: The study tested whether susceptible B10.TCRδ⁻/⁻ mice have dry eyes compared with...
6.
Born W, Zhang L, Nakayama M, Jin N, Chain J, Huang Y, et al.
Cell Mol Life Sci . 2011 May; 68(14):2335-43. PMID: 21553233
γδ T cells express adaptive antigen receptors encoded by rearranging genes. Their diversity is highest in the small region of TCR V-J junctions, especially in the δ chain, which should...
7.
Aydintug M, Roark C, Chain J, Born W, OBrien R
Mol Immunol . 2008 May; 45(11):3253-63. PMID: 18455236
As only a handful of ligands have been identified, the general nature of the ligands recognized by gammadelta T cells remains unresolved. In this study, soluble multimerized gammadelta T cell...
8.
OBrien R, Roark C, Jin N, Aydintug M, French J, Chain J, et al.
Immunol Rev . 2007 Feb; 215:77-88. PMID: 17291280
The gammadelta T-cell receptors (TCRs) are limited in their diversity, suggesting that their natural ligands may be few in number. Ligands for gammadeltaTCRs that have thus far been determined are...
9.
Joachims M, Chain J, Hooker S, Knott-Craig C, Thompson L
J Immunol . 2006 Jan; 176(3):1543-52. PMID: 16424183
To evaluate the role of the TCR in the alphabeta/gammadelta lineage choice during human thymocyte development, molecular analyses of the TCRbeta locus in gammadelta cells and the TCRgamma and delta...