Jennifer C Utting
Overview
Explore the profile of Jennifer C Utting including associated specialties, affiliations and a list of published articles.
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6
Citations
432
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Recent Articles
1.
Hypothermia inhibits osteoblast differentiation and bone formation but stimulates osteoclastogenesis
Patel J, Utting J, Key M, Orriss I, Taylor S, Whatling P, et al.
Exp Cell Res
. 2012 Jul;
318(17):2237-44.
PMID: 22771842
It has long been known that core body temperature declines with age, with temperatures of 35.5°C or below common in the elderly. However, the effects of temperature reduction on bone...
2.
Utting J, Flanagan A, Brandao-Burch A, Orriss I, Arnett T
Cell Biochem Funct
. 2010 Jun;
28(5):374-80.
PMID: 20556743
Active pathological bone destruction in humans often occurs in locations where oxygen tension (pO(2)) is likely to be low, for example, at the sites of tumours, inflammation, infections and fractures,...
3.
Orriss I, Knight G, Utting J, Taylor S, Burnstock G, Arnett T
J Cell Physiol
. 2009 Mar;
220(1):155-62.
PMID: 19259945
Many neuronal and non-neuronal cell types release ATP in a controlled manner. After release, extracellular ATP (or, following hydrolysis, ADP) acts on cells in a paracrine manner via P2 receptors....
4.
Orriss I, Utting J, Brandao-Burch A, Colston K, Grubb B, Burnstock G, et al.
Endocrinology
. 2007 Jun;
148(9):4208-16.
PMID: 17569759
Extracellular nucleotides, signaling through P2 receptors, may act as local regulators of bone cell function. We investigated the effects of nucleotide agonists [ATP, ADP, uridine triphosphate (UTP), and uridine diphosphate]...
5.
Spencer G, Utting J, Etheridge S, Arnett T, Genever P
J Cell Sci
. 2006 Mar;
119(Pt 7):1283-96.
PMID: 16522681
Reports implicating Wnt signalling in the regulation of bone mass have prompted widespread interest in the use of Wnt mimetics for the treatment of skeletal disorders. To date much of...
6.
Arnett T, Gibbons D, Utting J, Orriss I, Hoebertz A, Rosendaal M, et al.
J Cell Physiol
. 2003 May;
196(1):2-8.
PMID: 12767036
Hypoxia is known to act as a general stimulator of cells derived from marrow precursors. We investigated the effect of oxygen tension on the formation and function of osteoclasts, the...