Jennifer Arthur Ataam
Overview
Explore the profile of Jennifer Arthur Ataam including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
183
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Recent Articles
1.
Arthur Ataam J, Belbachir N, Perea-Gil I, Termglinchan V, Vadgama N, Garg P, et al.
Circ Genom Precis Med
. 2024 May;
17(3):e004526.
PMID: 38752368
No abstract available.
2.
Cheawsamoot C, Ramchandani R, Ameen M, Arthur Ataam J, Khongphatthanayothin A, Shotelersuk V, et al.
Stem Cell Res
. 2023 Nov;
73:103233.
PMID: 37944352
Loss of function variants in ALPK3 have been associated with dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM). However, the underlying pathomechanism remain largely unknown. Here, we generated human iPSC lines...
3.
Prunicki M, Cauwenberghs N, Arthur Ataam J, Movassagh H, Kim J, Kuznetsova T, et al.
Environ Health
. 2022 Nov;
21(1):117.
PMID: 36443731
No abstract available.
4.
Perea-Gil I, Seeger T, Bruyneel A, Termglinchan V, Monte E, Lim E, et al.
Eur Heart J
. 2022 Jun;
43(36):3477-3489.
PMID: 35728000
Aims: Genetic dilated cardiomyopathy (DCM) is a leading cause of heart failure. Despite significant progress in understanding the genetic aetiologies of DCM, the molecular mechanisms underlying the pathogenesis of familial...
5.
Metzl-Raz E, Bharucha N, Arthur Ataam J, Gavidia A, Greenleaf W, Karakikes I
Stem Cell Res
. 2022 Mar;
61:102754.
PMID: 35325819
Temporal regulation of CRISPRi activity is critical for genetic screens. Here, we present an inducible CRISPRi platform enabling selection of iPSC-derived cardiomyocytes and reversible gene knockdown. We targeted a doxycycline-inducible...
6.
Martinez E, Li J, Arthur Ataam J, Tokarski K, Thakur H, Karakikes I, et al.
Gene Ther
. 2022 Feb;
30(7-8):543-551.
PMID: 35102273
Ischemic cardiomyopathy is a leading cause of death and an unmet clinical need. Adeno-associated virus (AAV) gene-based therapies hold great promise for treating and preventing heart failure. Previously we showed...
7.
Haddad F, Arthur Ataam J, Amsallem M, Cauwenberghs N, Kuznetsova T, Rosenberg-Hasson Y, et al.
J Card Fail
. 2022 Jan;
28(6):935-946.
PMID: 34979242
Background: The insulin-like growth factor (IGF) axis emerged as an important pathway in heart failure with preserved ejection (HFpEF). We aimed to identify IGF phenotypes associated with HFpEF in the...
8.
Bharucha N, Arthur Ataam J, Gavidia A, Karakikes I
Stem Cell Res
. 2021 Dec;
57:102610.
PMID: 34875545
Prime editing uses the Cas9 nickase fused to a reverse transcriptase to copy a DNA sequence into a specific locus from a 'prime editing' guide RNA (pegRNA), eliminating the need...
9.
Haddad F, Contrepois K, Amsallem M, Denault A, Bernardo R, Jha A, et al.
Chest
. 2021 Nov;
161(5):1347-1359.
PMID: 34774527
Background: Prognosis in pulmonary arterial hypertension (PAH) is closely related to indexes of right ventricular function. A better understanding of their relationship may provide important implications for risk stratification in...
10.
Feyen D, Perea-Gil I, Maas R, Harakalova M, Gavidia A, Arthur Ataam J, et al.
Circulation
. 2021 Apr;
144(5):382-392.
PMID: 33928785
Background: Phospholamban (PLN) is a critical regulator of calcium cycling and contractility in the heart. The loss of arginine at position 14 in PLN (R14del) is associated with dilated cardiomyopathy...