Jennifer A C van Hulst
Overview
Explore the profile of Jennifer A C van Hulst including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
125
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Neys S, Heutz J, van Hulst J, Vink M, Bergen I, de Jong P, et al.
J Autoimmun
. 2024 Feb;
143:103168.
PMID: 38350168
Objective: Altered B cell receptor (BCR) signaling has been implicated in the pathogenesis of rheumatoid arthritis (RA). Here we aimed to identify signaling aberrations in autoantibody-positive and autoantibody-negative RA patients...
2.
van Uden D, Koudstaal T, van Hulst J, Vink M, van Nimwegen M, van den Toorn L, et al.
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35742956
Pulmonary arterial hypertension (PAH) is rare disease that is categorized as idiopathic (IPAH) when no underlying cause can be identified. Lungs of most patients with IPAH contain increased numbers of...
3.
van Uden D, Koudstaal T, van Hulst J, van den Bosch T, Vink M, Bergen I, et al.
Front Immunol
. 2022 May;
13:861450.
PMID: 35572511
Introduction: Previous studies have shown an increase of T cells and chemokines in vascular lesions of patients with chronic thromboembolic pulmonary hypertension (CTEPH). However, detailed characterization of these T cells...
4.
Rip J, de Bruijn M, Neys S, Singh S, Willar J, van Hulst J, et al.
Eur J Immunol
. 2021 Jul;
51(9):2251-2265.
PMID: 34323286
Bruton's tyrosine kinase (Btk) is a crucial signaling molecule in BCR signaling and a key regulator of B- cell differentiation and function. Btk inhibition has shown impressive clinical efficacy in...
5.
Aberrant B Cell Receptor Signaling in Naïve B Cells from Patients with Idiopathic Pulmonary Fibrosis
Neys S, Heukels P, van Hulst J, Rip J, Wijsenbeek M, Hendriks R, et al.
Cells
. 2021 Jun;
10(6).
PMID: 34073225
Idiopathic pulmonary fibrosis (IPF) is a chronic and ultimately fatal disease in which an impaired healing response to recurrent micro-injuries is thought to lead to fibrosis. Recent findings hint at...
6.
Heukels P, Corneth O, van Uden D, van Hulst J, van den Toorn L, van den Bosch A, et al.
Thorax
. 2021 May;
76(12):1209-1218.
PMID: 33963088
Introduction: Autoreactivity against pulmonary vascular structures is thought to be involved in idiopathic pulmonary arterial hypertension (IPAH), but the underlying mechanisms remain poorly understood. We hypothesised that aberrant B-cell activation...
7.
van Uden D, Koudstaal T, van Hulst J, Bergen I, Gootjes C, Morrell N, et al.
Int J Mol Sci
. 2021 Feb;
22(4).
PMID: 33578743
The pathogenesis of idiopathic pulmonary arterial hypertension (IPAH) is not fully understood, but evidence is accumulating that immune dysfunction plays a significant role. We previously reported that 31-week-old mice develop...
8.
Koudstaal T, van Hulst J, Das T, Neys S, Merkus D, Bergen I, et al.
Am J Respir Cell Mol Biol
. 2020 Aug;
63(5):665-680.
PMID: 32755457
Chronic perivascular inflammation is a prominent feature in the lungs of idiopathic pulmonary arterial hypertension. Although the proportions of conventional dendritic cells (cDCs) and plasmacytoid DCs are increased in idiopathic...
9.
Vroman H, van Uden D, Bergen I, van Hulst J, Lukkes M, van Loo G, et al.
Allergy
. 2020 Apr;
75(10):2587-2598.
PMID: 32329078
Background: Conventional type 1 dendritic cells (cDC1s) control anti-viral and anti-tumor immunity by inducing antigen-specific cytotoxic CD8 T-cell responses. Controversy exists whether cDC1s also control CD4 T helper 2 (Th2)...
10.
Heukels P, van Hulst J, van Nimwegen M, Boorsma C, Melgert B, von der Thusen J, et al.
Respir Res
. 2019 Oct;
20(1):232.
PMID: 31651327
Rationale: Idiopathic Pulmonary Fibrosis (IPF) is thought to be triggered by repeated alveolar epithelial cell injury. Current evidence suggests that aberrant immune activation may contribute. However, the role of B-cell...