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Jenna L N Sprowles

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Recent Articles
1.
Enright E, Eick S, Morello-Frosch R, Aguiar A, Woodbury M, Sprowles J, et al.
Neurotoxicol Teratol . 2023 May; 98:107182. PMID: 37172619
Background: Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) has been linked to a wide array of adverse maternal and child health outcomes. However, studies examining PFAS in relation to...
2.
Nozadi S, Li X, Kong X, Rennie B, Kanda D, MacKenzie D, et al.
Int J Environ Res Public Health . 2023 Jan; 20(2). PMID: 36673770
Background: The financial hardships and social isolation experienced during the COVID-19 pandemic have been found to adversely affect children's developmental outcomes. While many studies thus far have focused on school-aged...
3.
Brennan P, Dunlop A, Croen L, Avalos L, Salisbury A, Hipwell A, et al.
Res Child Adolesc Psychopathol . 2022 Nov; 51(4):513-527. PMID: 36417100
Prenatal antidepressant exposure has been associated with increased risk for neurodevelopmental disorders in childhood, including autism spectrum disorder (ASD). The current study utilized multi-cohort data from the Environmental influences on...
4.
Sprowles J, Dzwilewski K, Merced-Nieves F, Musaad S, Schantz S, Geiger S
Neurotoxicol Teratol . 2022 May; 92:107102. PMID: 35588931
Phthalates are ubiquitous endocrine-disrupting chemicals, and research indicates that prenatal exposure to some phthalates may affect neurodevelopment. In a prospective birth cohort study, five first-morning urine samples collected across pregnancy...
5.
Sprowles J, Monaikul S, Aguiar A, Gardiner J, Monaikul N, Kostyniak P, et al.
Neurotoxicol Teratol . 2022 Apr; 92:107092. PMID: 35472414
Polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) are ubiquitous environmental chemicals that have long half-lives. Humans are exposed to PCBs and PBDEs mainly through diet, and relative to other...
6.
Sprowles J, Vorhees C, Williams M
Neurotoxicol Teratol . 2021 Feb; 84:106956. PMID: 33524508
Two developmental stressors were compared in preweaning rats exposed to either one stressor or both. Stressors were barren cage rearing or maternal separation (pup isolation). 40 gravid Sprague-Dawley CD/IGS rats...
7.
Hufgard J, Sprowles J, Pitzer E, Koch S, Jiang M, Wang Q, et al.
J Appl Toxicol . 2018 Dec; 39(4):603-621. PMID: 30561030
Polychlorinated biphenyls (PCBs) are toxic environmental pollutants. Humans are exposed to PCB mixtures via contaminated food or water. PCB exposure causes adverse effects in adults and after exposure in utero....
8.
Sprowles J, Amos-Kroohs R, Braun A, Sugimoto C, Vorhees C, Williams M
Neurotoxicol Teratol . 2018 Apr; 67:50-64. PMID: 29631003
Developmental stress, including low socioeconomic status (SES), can induce dysregulation of the hypothalamic-pituitary-adrenal axis and result in long-term changes in stress reactivity. Children in lower SES households experience more stress...
9.
Sprowles J, Hufgard J, Gutierrez A, Bailey R, Jablonski S, Williams M, et al.
Int J Dev Neurosci . 2017 Jun; 61:92-111. PMID: 28655626
Most antidepressants inhibit monoamine reuptake. Selective serotonin (5-HT) reuptake inhibitors (SSRIs) act on the 5-HT transporter (SERT) whereas norepinephrine-dopamine reuptake inhibitors (NDRIs) act on the norepinephrine and dopamine transporters. Epidemiological...
10.
Miller M, Sprowles J, Voeller J, Meyer A, Sable H
Neurotoxicol Teratol . 2017 May; 62:34-41. PMID: 28465083
Polychlorinated biphenyls (PCBs) are ubiquitous environmental toxicants known to adversely affect the nervous system and more specifically the dopamine system. Developmental PCB exposure in rats has been shown to produce...