Jenna L Balestrini
Overview
Explore the profile of Jenna L Balestrini including associated specialties, affiliations and a list of published articles.
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18
Citations
709
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Recent Articles
1.
Lissandrello C, Santos J, Hsi P, Welch M, Mott V, Kim E, et al.
Sci Rep
. 2020 Oct;
10(1):18045.
PMID: 33093518
Implementation of gene editing technologies such as CRISPR/Cas9 in the manufacture of novel cell-based therapeutics has the potential to enable highly-targeted, stable, and persistent genome modifications without the use of...
2.
Hsi P, Christianson R, Dubay R, Lissandrello C, Fiering J, Balestrini J, et al.
Lab Chip
. 2019 Aug;
19(18):2978-2992.
PMID: 31410419
Autologous cellular therapies based on modifying T cells to express chimeric antigen receptor genes have been highly successful in treating hematological cancers. Deployment of these therapies is limited by the...
3.
Polio S, Stasiak S, Jamieson R, Balestrini J, Krishnan R, Parameswaran H
Sci Rep
. 2019 Jul;
9(1):9564.
PMID: 31267003
For an airway or a blood vessel to narrow, there must be a connected path that links the smooth muscle (SM) cells with each other, and transmits forces around the...
4.
Li C, Talele N, Boo S, Koehler A, Knee-Walden E, Balestrini J, et al.
Nat Mater
. 2016 Nov;
16(3):379-389.
PMID: 27798620
Expansion on stiff culture substrates activates pro-fibrotic cell programs that are retained by mechanical memory. Here, we show that priming on physiologically soft silicone substrates suppresses fibrogenesis and desensitizes mesenchymal...
5.
Dimitrievska S, Gui L, Weyers A, Lin T, Cai C, Wu W, et al.
Arterioscler Thromb Vasc Biol
. 2016 Jul;
36(9):1847-53.
PMID: 27386939
Objective: It is widely accepted that the presence of a glycosaminoglycan-rich glycocalyx is essential for endothelialized vasculature health; in fact, a damaged or impaired glycocalyx has been demonstrated in many...
6.
Balestrini J, Gard A, Gerhold K, Wilcox E, Liu A, Schwan J, et al.
Biomaterials
. 2016 Jun;
102:220-30.
PMID: 27344365
Lung engineering is a promising technology, relying on re-seeding of either human or xenographic decellularized matrices with patient-derived pulmonary cells. Little is known about the species-specificity of decellularization in various...
7.
Huang A, Balestrini J, Udelsman B, Zhou K, Zhao L, Ferruzzi J, et al.
Tissue Eng Part C Methods
. 2016 Apr;
22(6):524-33.
PMID: 27108525
Tissue-engineered blood vessels (TEVs) are typically produced using the pulsatile, uniaxial circumferential stretch to mechanically condition and strengthen the arterial grafts. Despite improvements in the mechanical integrity of TEVs after...
8.
Raredon M, Rocco K, Gheorghe C, Sivarapatna A, Ghaedi M, Balestrini J, et al.
Biores Open Access
. 2016 Apr;
5(1):72-83.
PMID: 27088061
Decellularized organs are now established as promising scaffolds for whole-organ regeneration. For this work to reach therapeutic practice, techniques and apparatus are necessary for doing human-scale clinically applicable organ cultures....
9.
Sun H, Zhu Y, Pan H, Chen X, Balestrini J, Lam T, et al.
Arthritis Rheumatol
. 2016 Jan;
68(5):1251-61.
PMID: 26749424
Objective: Fibrocytes are collagen-producing leukocytes that accumulate in patients with systemic sclerosis (SSc; scleroderma)-related interstitial lung disease (ILD) via unknown mechanisms that have been associated with altered expression of neuroimmune...
10.
Balestrini J, Liu A, Gard A, Huie J, Blatt K, Schwan J, et al.
Tissue Eng Part C Methods
. 2015 Dec;
22(3):260-9.
PMID: 26697757
Lung engineering is a potential alternative to transplantation for patients with end-stage pulmonary failure. Two challenges critical to the successful development of an engineered lung developed from a decellularized scaffold...