Jen-Yang Chen
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Explore the profile of Jen-Yang Chen including associated specialties, affiliations and a list of published articles.
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71
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Recent Articles
1.
Wu C, Chen M, Chen J
Biomedicines
. 2024 Mar;
12(3).
PMID: 38540100
Nasopharyngeal carcinoma (NPC) is a malignancy prevailing in Taiwan, Hong Kong, Southern China, Southeast Asia, and North Africa. Although early-stage NPC responds well to the primary treatment of radio-chemotherapy, the...
2.
Wu C, Chen M, Lee T, Huang T, Cho D, Chen J
Viral Immunol
. 2024 Mar;
37(2):115-123.
PMID: 38498796
Nasopharyngeal carcinoma (NPC) is a specific human malignancy with unique geographic distribution and genetic backgrounds. Although early treatment with radio-chemotherapy has been proven effective for NPC therapy, its therapeutic efficacy...
3.
Screening and identification of emodin as an EBV DNase inhibitor to prevent its biological functions
Wu C, Chen M, Lee T, Cheng Y, Tsou H, Huang T, et al.
Virol J
. 2023 Jul;
20(1):148.
PMID: 37443068
Background: The Epstein-Barr virus (EBV) is a prevalent oncovirus associated with a variety of human illnesses. BGLF5, an EBV DNase with alkaline nuclease (AN) activity, plays important roles in the...
4.
Wu C, Lee T, Cheng Y, Cho D, Chen J
Molecules
. 2022 Dec;
27(23).
PMID: 36500249
Kaempferol (KP, 3,4',5,7-tetrahydroxyflavone), a dietary flavonol, has anti-cancer, antioxidant, anti-inflammatory, antimicrobial, and antimutagenic functions. However, it is unknown whether kaempferol possesses anti-Epstein-Barr virus (EBV) activity. Previously, we demonstrated that inhibition...
5.
Wu C, Chen M, Cheng Y, Ko Y, Lin S, Chiu I, et al.
Cancers (Basel)
. 2019 Nov;
11(11).
PMID: 31731581
Nasopharyngeal carcinoma (NPC) is a unique malignancy derived from the epithelium of the nasopharynx. Despite great advances in the development of radiotherapy and chemotherapy, relapse and metastasis in NPC patients...
6.
Wu C, Fang C, Huang S, Chiu S, Lee C, Chen J
Cancers (Basel)
. 2018 Apr;
10(4).
PMID: 29673164
Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma derived from the epithelium of the post-nasal cavity, with a unique geographic and ethnic distribution. Epstein–Barr virus (EBV) is an etiological agent...
7.
Huang S, Wu C, Cheng Y, Chou S, Jiang Y, Chu K, et al.
Oncotarget
. 2017 Nov;
8(45):78948-78964.
PMID: 29108278
Nasopharyngeal carcinoma (NPC) is a serious health problem in China and Southeast Asia. Relapse is the major cause of mortality, but mechanisms of relapse are mysterious. Epstein-Barr virus (EBV) reactivation...
8.
Chen Y, Chen Y, Chang Y, Wu C, Ko Y, Tsao S, et al.
J Virol
. 2017 May;
91(15).
PMID: 28490592
Rta, an Epstein-Barr virus (EBV) immediate-early protein, reactivates viral lytic replication that is closely associated with tumorigenesis. In previous studies, we demonstrated that in epithelial cells Rta efficiently induced cellular...
9.
Wu C, Fang C, Cheng Y, Hsu H, Chou S, Huang S, et al.
J Biomed Sci
. 2017 Jan;
24(1):2.
PMID: 28056971
Background: Lytic reactivation of EBV has been reported to play an important role in human diseases, including NPC carcinogenesis. Inhibition of EBV reactivation is considered to be of great benefit...
10.
Lo Y, Pan W, Hsu W, Chien Y, Chen J, Hsu M, et al.
PLoS One
. 2016 Jun;
11(6):e0155892.
PMID: 27249558
Evidence on the association between dietary component, dietary pattern and nasopharyngeal carcinoma (NPC) is scarce. A major challenge is the high degree of correlation among dietary constituents. We aimed to...