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Jemma E Cook

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Recent Articles
1.
Sharmin D, Ruedi-Bettschen D, Berro L, Cook J, Reeves-Darby J, Pareek T, et al.
J Psychopharmacol . 2024 Oct; 38(12):1157-1169. PMID: 39385515
Background: Benzodiazepines bind to γ-aminobutyric acid type A (GABA) receptor subtypes identified by different α subunits (i.e., α1GABA, α2GABA, α3GABA, and α5GABA). Sedative-motor effects of benzodiazepines are thought to involve...
2.
Cook J, Platt D, Ruedi-Bettschen D, Rowlett J
Front Psychiatry . 2023 May; 14:1142531. PMID: 37252149
Introduction: Benzodiazepines (BZs) are prescribed as anxiolytics, but their use is limited by side effects including abuse liability and daytime drowsiness. Neuroactive steroids are compounds that, like BZs, modulate the...
3.
Yensen C, Nighbor T, Cook J, Oliver A, Lattal K
Behav Processes . 2021 Dec; 195:104567. PMID: 34929305
The effects of local periods of extinction on resurgence following transitions from variable-interval (VI) to fixed-interval (FI) schedules were studied using four pigeons exposed to a within-session resurgence procedure. Each...
4.
Pfund R, Cook J, McAfee N, Huskinson S, Parker J
Prof Psychol Res Pr . 2021 Aug; 52(2):137-145. PMID: 34421192
A growing empirical literature supports contingency management (CM) as an efficacious treatment for substance use disorders, especially when reinforcers are immediate, frequent, and of sufficient magnitude on escalating schedules. However,...
5.
Nighbor T, Cook J, Oliver A, Lattal K
Behav Processes . 2020 Oct; 181:104257. PMID: 33002565
Following lever-press training on variable-interval 30-s schedules, rats were exposed to three types of schedules designed to eliminate lever pressing. The first two were variations on what is called a...
6.
Lattal K, Kuroda T, Cook J
J Exp Anal Behav . 2020 Jul; 114(1):47-59. PMID: 32639050
The occurrence of extinction bursts-transient increases in response rate in excess of those observed in baseline during the period immediately following discontinuation of reinforcement of a response-was examined. In Experiment...
7.
Cook J, Chandler C, Ruedi-Bettschen D, Taylor I, Patterson S, Platt D
Psychol Addict Behav . 2019 Nov; 34(1):10-22. PMID: 31750701
Resurgence may be a mechanism of relapse in alcohol use disorder patients upon discharge from treatment as part of an abuse-treatment-relapse cycle. Adjunctive pharmacotherapies may be a means to facilitate...
8.
Meng Z, Berro L, Sawyer E, Ruedi-Bettschen D, Cook J, Li G, et al.
J Psychopharmacol . 2019 Nov; 34(3):348-357. PMID: 31670615
Background: In recent years, pharmacological strategies have implicated α3 subunit-containing GABA (α3GABA) receptor subtypes in the anxiety-reducing effects of benzodiazepines, whereas transgenic mouse approaches have implicated α2 or α5 subunit-containing...
9.
Berro L, Ruedi-Bettschen D, Cook J, Golani L, Li G, Jahan R, et al.
Alcohol Clin Exp Res . 2019 Mar; 43(5):791-802. PMID: 30861153
Background: Previous studies have investigated α1GABA and α5GABA receptor mechanisms in the behavioral effects of ethanol (EtOH) in monkeys. However, genetic studies in humans and preclinical studies with mutant mice...
10.
Gerb S, Cook J, Gochenauer A, Young C, Fulton L, Grady A, et al.
Comp Med . 2019 Jan; 69(1):29-34. PMID: 30696519
Ketamine is one of the most commonly used anesthetics in human and veterinary medicine, but its clinical effectiveness is often compromised due to tolerance to its anesthetic effects. Although ketamine...